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Therapeutic Targeting of Pancreatic Cancer via EphA2 Dimeric Agonistic Agents

Recently, we reported on potent EphA2 targeting compounds and demonstrated that dimeric versions of such agents can exhibit remarkably increased agonistic activity in cellular assays compared to the monomers. Here we further characterize the activity of dimeric compounds at the structural, biochemic...

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Bibliographic Details
Published in:Pharmaceuticals (Basel)
Main Authors: Salem, Ahmed F., Gambini, Luca, Udompholkul, Parima, Baggio, Carlo, Pellecchia, Maurizio
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281375/
https://ncbi.nlm.nih.gov/pubmed/32397624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13050090
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