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Potent and selective EphA4 agonists for the treatment of ALS
Amyotrophic lateral sclerosis (ALS) is a progressive degenerative disease that affects motor neurons. Recent studies identified the receptor tyrosine kinase EphA4 as a disease-modifying gene, critical for the progression of motor neuron degeneration. We report on the design and characterization of a...
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| Publicado no: | Cell Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522132/ https://ncbi.nlm.nih.gov/pubmed/28196613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.01.006 |
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