NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease**

The NMR spectrum of a mixture of small molecules is a fingerprint of all of its components. Herein, we present an NMR fingerprint method that takes advantage of the fact that fractions contain simplified NMR profiles, with minimal signal overlap, to allow the identification of unique spectral patter...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Grkovic, Tanja, Pouwer, Rebecca H, Vial, Marie-Laure, Gambini, Luca, Noël, Alba, Hooper, John N A, Wood, Stephen A, Mellick, George D, Quinn, Ronald J
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2014
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298794/
https://ncbi.nlm.nih.gov/pubmed/24737726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201402239
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