NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease**

The NMR spectrum of a mixture of small molecules is a fingerprint of all of its components. Herein, we present an NMR fingerprint method that takes advantage of the fact that fractions contain simplified NMR profiles, with minimal signal overlap, to allow the identification of unique spectral patter...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Grkovic, Tanja, Pouwer, Rebecca H, Vial, Marie-Laure, Gambini, Luca, Noël, Alba, Hooper, John N A, Wood, Stephen A, Mellick, George D, Quinn, Ronald J
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag 2014
Fag:
Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298794/
https://ncbi.nlm.nih.gov/pubmed/24737726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201402239
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