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NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson’s Disease**

The NMR spectrum of a mixture of small molecules is a fingerprint of all of its components. Herein, we present an NMR fingerprint method that takes advantage of the fact that fractions contain simplified NMR profiles, with minimal signal overlap, to allow the identification of unique spectral patter...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Grkovic, Tanja, Pouwer, Rebecca H, Vial, Marie-Laure, Gambini, Luca, Noël, Alba, Hooper, John N A, Wood, Stephen A, Mellick, George D, Quinn, Ronald J
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298794/
https://ncbi.nlm.nih.gov/pubmed/24737726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201402239
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