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Human resistin protects against endotoxic shock by blocking LPS–TLR4 interaction

Helminths trigger multiple immunomodulatory pathways that can protect from sepsis. Human resistin (hRetn) is an immune cell-derived protein that is highly elevated in helminth infection and sepsis. However, the function of hRetn in sepsis, or whether hRetn influences helminth protection against seps...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jang, Jessica C., Li, Jiang, Gambini, Luca, Batugedara, Hashini M., Sati, Sandeep, Lazar, Mitchell A., Fan, Li, Pellecchia, Maurizio, Nair, Meera G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715788/
https://ncbi.nlm.nih.gov/pubmed/29133417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716015114
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