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Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming

Processing of certain viral proteins and bacterial toxins by host serine proteases is a frequent and critical step in virulence. The coronavirus spike glycoprotein contains three (S1, S2, and S2′) cleavage sites that are processed by human host proteases. The exact nature of these cleavage sites, an...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Barile, Elisa, Baggio, Carlo, Gambini, Luca, Shiryaev, Sergey A., Strongin, Alex Y., Pellecchia, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287953/
https://ncbi.nlm.nih.gov/pubmed/32455942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102424
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