The TMEM16 Protein Family: A New Class of Chloride Channels?

Por Galietta, Luis J.V.
Publicado em 2009

TMEM16 Proteins: Membrane Channels with Unusual Pores

Por Galietta, Luis J.V.
Publicado no Biophys J (2016)

Pharmacological Correctors of Mutant CFTR Mistrafficking

Por Pedemonte, Nicoletta, Galietta, Luis J. V.
Publicado em 2012

Chloride channels as drug targets

Por Verkman, Alan S., Galietta, Luis J. V.
Publicado em 2008

Modulation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity and Genistein Binding by Cytosolic pH

Por Melani, Raffaella, Tomati, Valeria, Galietta, Luis J. V., Zegarra-Moran, Olga
Publicado em 2010

Intermolecular Interactions in the TMEM16A Dimer Controlling Channel Activity

Por Scudieri, Paolo, Musante, Ilaria, Gianotti, Ambra, Moran, Oscar, Galietta, Luis J. V.
Publicado no Sci Rep (2016)

Insensitivity of volume-sensitive chloride currents to chromones in human airway epithelial cells

Por Zegarra-Moran, Olga, Lantero, Sabina, Sacco, Oliviero, Rossi, Giovanni A, Galietta, Luis J V
Publicado em 1998

NANOMOLAR CFTR INHIBITION BY PORE-OCCLUDING DIVALENT POLYETHYLENE GLYCOL-MALONIC ACID HYDRAZIDES

Por Sonawane, N.D., Zhao, Dan, Zegarra-Moran, Olga, Galietta, Luis J.V., Verkman, A.S.
Publicado em 2008

Discovery of Glycine Hydrazide Pore-occluding CFTR Inhibitors: Mechanism, Structure–Activity Analysis, and In Vivo Efficacy

Por Muanprasat, Chatchai, Sonawane, N.D., Salinas, Danieli, Taddei, Alessandro, Galietta, Luis J.V., Verkman, A.S.
Publicado em 2004

Block of CFTR-dependent chloride currents by inhibitors of multidrugresistance-associated proteins

Por Diena, Tullia, Melani, Raffaella, Caci, Emanuela, Pedemonte, Nicoletta, Sondo, Elvira, Zegarra-Moran, Olga, Galietta, Luis J.V.
Publicado em 2007

RESCUE OF THE MUTANT CFTR CHLORIDE CHANNEL BY PHARMACOLOGICAL CORRECTORS AND LOW TEMPERATURE ANALYZED BY GENE EXPRESSION PROFILING

Por Sondo, Elvira, Tomati, Valeria, Caci, Emanuela, Esposito, Alessia Isabella, Pfeffer, Ulrich, Pedemonte, Nicoletta, Galietta, Luis J.V.
Publicado em 2011

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion

Por Ma, Tonghui, Thiagarajah, Jay R., Yang, Hong, Sonawane, Nitin D., Folli, Chiara, Galietta, Luis J.V., Verkman, A.S.
Publicado em 2002

Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening

Por Pedemonte, Nicoletta, Lukacs, Gergely L., Du, Kai, Caci, Emanuela, Zegarra-Moran, Olga, Galietta, Luis J.V., Verkman, A.S.
Publicado em 2005

Cystic Fibrosis: A New Target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines

Por Budriesi, Roberta, Ioan, Pierfranco, Leoni, Alberto, Pedemonte, Nicoletta, Locatelli, Alessandra, Micucci, Matteo, Chiarini, Alberto, Galietta, Luis J. V.
Publicado em 2011

Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia

Por Veit, Guido, Bossard, Florian, Goepp, Julie, Verkman, A. S., Galietta, Luis J. V., Hanrahan, John W., Lukacs, Gergely L.
Publicado em 2012

Non-canonical translation start sites in the TMEM16A chloride channel()

Por Sondo, Elvira, Scudieri, Paolo, Tomati, Valeria, Caci, Emanuela, Mazzone, Amelia, Farrugia, Gianrico, Ravazzolo, Roberto, Galietta, Luis J.V.
Publicado em 2014

Regulation of TMEM16A Chloride Channel Properties by Alternative Splicing

Por Ferrera, Loretta, Caputo, Antonella, Ubby, Ifeoma, Bussani, Erica, Zegarra-Moran, Olga, Ravazzolo, Roberto, Pagani, Franco, Galietta, Luis J. V.
Publicado em 2009

A minimal isoform of the TMEM16A protein associated with chloride channel activity

Por Ferrera, Loretta, Scudieri, Paolo, Sondo, Elvira, Caputo, Antonella, Caci, Emanuela, Zegarra-Moran, Olga, Ravazzolo, Roberto, Galietta, Luis J.V.
Publicado em 2011

Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms

Por Scudieri, Paolo, Caci, Emanuela, Venturini, Arianna, Sondo, Elvira, Pianigiani, Giulia, Marchetti, Carla, Ravazzolo, Roberto, Pagani, Franco, Galietta, Luis J V
Publicado no J Physiol (2015)

Dual Activity of Aminoarylthiazoles on the Trafficking and Gating Defects of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Caused by Cystic Fibrosis Muta...

Por Pedemonte, Nicoletta, Tomati, Valeria, Sondo, Elvira, Caci, Emanuela, Millo, Enrico, Armirotti, Andrea, Damonte, Gianluca, Zegarra-Moran, Olga, Galietta, Luis J. V.
Publicado em 2011