High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation

by Sondo, Elvira, Bertelli, Roberta, Pesce, Emanuela, Ghiggeri, Gian Marco, Pedemonte, Nicoletta
Published in Front Immunol (2019)

Block of CFTR-dependent chloride currents by inhibitors of multidrugresistance-associated proteins

by Diena, Tullia, Melani, Raffaella, Caci, Emanuela, Pedemonte, Nicoletta, Sondo, Elvira, Zegarra-Moran, Olga, Galietta, Luis J.V.
Published 2007

RESCUE OF THE MUTANT CFTR CHLORIDE CHANNEL BY PHARMACOLOGICAL CORRECTORS AND LOW TEMPERATURE ANALYZED BY GENE EXPRESSION PROFILING

by Sondo, Elvira, Tomati, Valeria, Caci, Emanuela, Esposito, Alessia Isabella, Pfeffer, Ulrich, Pedemonte, Nicoletta, Galietta, Luis J.V.
Published 2011

Non-canonical translation start sites in the TMEM16A chloride channel()

by Sondo, Elvira, Scudieri, Paolo, Tomati, Valeria, Caci, Emanuela, Mazzone, Amelia, Farrugia, Gianrico, Ravazzolo, Roberto, Galietta, Luis J.V.
Published 2014

A minimal isoform of the TMEM16A protein associated with chloride channel activity

by Ferrera, Loretta, Scudieri, Paolo, Sondo, Elvira, Caputo, Antonella, Caci, Emanuela, Zegarra-Moran, Olga, Ravazzolo, Roberto, Galietta, Luis J.V.
Published 2011

Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms

by Scudieri, Paolo, Caci, Emanuela, Venturini, Arianna, Sondo, Elvira, Pianigiani, Giulia, Marchetti, Carla, Ravazzolo, Roberto, Pagani, Franco, Galietta, Luis J V
Published in J Physiol (2015)

Dual Activity of Aminoarylthiazoles on the Trafficking and Gating Defects of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Caused by Cystic Fibrosis Muta...

by Pedemonte, Nicoletta, Tomati, Valeria, Sondo, Elvira, Caci, Emanuela, Millo, Enrico, Armirotti, Andrea, Damonte, Gianluca, Zegarra-Moran, Olga, Galietta, Luis J. V.
Published 2011

High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel

by Tomati, Valeria, Pesce, Emanuela, Caci, Emanuela, Sondo, Elvira, Scudieri, Paolo, Marini, Monica, Amato, Felice, Castaldo, Giuseppe, Ravazzolo, Roberto, Galietta, Luis J. V., Pedemonte, Nicoletta
Published in J Biol Chem (2018)

Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia

by Scudieri, Paolo, Caci, Emanuela, Bruno, Silvia, Ferrera, Loretta, Schiavon, Marco, Sondo, Elvira, Tomati, Valeria, Gianotti, Ambra, Zegarra-Moran, Olga, Pedemonte, Nicoletta, Rea, Federico, Ravazzolo, Roberto, Galietta, Luis J V
Published 2012

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

by Tomati, Valeria, Caci, Emanuela, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Cholon, Deborah M., Quinney, Nancy L., Boyles, Susan E., Armirotti, Andrea, Ravazzolo, Roberto, Galietta, Luis J.V., Gentzsch, Martina, Pedemonte, Nicoletta
Published in JCI Insight (2018)

The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism

by Pesce, Emanuela, Sondo, Elvira, Ferrera, Loretta, Tomati, Valeria, Caci, Emanuela, Scudieri, Paolo, Musante, Ilaria, Renda, Mario, Baatallah, Nesrine, Servel, Nathalie, Hinzpeter, Alexandre, di Bernardo, Diego, Pedemonte, Nicoletta, Galietta, Luis J. V.
Published in Front Pharmacol (2018)

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia

by Tomati, Valeria, Caci, Emanuela, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Cholon, Deborah M., Quinney, Nancy L., Boyles, Susan E., Armirotti, Andrea, Ravazzolo, Roberto, Galietta, Luis J.V., Gentzsch, Martina, Pedemonte, Nicoletta
Published in JCI Insight (2019)

Alternative Splicing at a NAGNAG Acceptor Site as a Novel Phenotype Modifier

by Hinzpeter, Alexandre, Aissat, Abdel, Sondo, Elvira, Costa, Catherine, Arous, Nicole, Gameiro, Christine, Martin, Natacha, Tarze, Agathe, Weiss, Laurence, de Becdelièvre, Alix, Costes, Bruno, Goossens, Michel, Galietta, Luis J., Girodon, Emmanuelle, Fanen, Pascale
Published 2010

Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin

by Caci, Emanuela, Scudieri, Paolo, Di Carlo, Emma, Morelli, Patrizia, Bruno, Silvia, De Fino, Ida, Bragonzi, Alessandra, Gianotti, Ambra, Sondo, Elvira, Ferrera, Loretta, Palleschi, Alessandro, Santambrogio, Luigi, Ravazzolo, Roberto, Galietta, Luis J. V.
Published in PLoS One (2015)

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel

by Pedemonte, Nicoletta, Bertozzi, Fabio, Caci, Emanuela, Sorana, Federico, Di Fruscia, Paolo, Tomati, Valeria, Ferrera, Loretta, Rodríguez-Gimeno, Alejandra, Berti, Francesco, Pesce, Emanuela, Sondo, Elvira, Gianotti, Ambra, Scudieri, Paolo, Bandiera, Tiziano, Galietta, Luis J. V.
Published in Sci Adv (2020)

Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment

by Capurro, Valeria, Tomati, Valeria, Sondo, Elvira, Renda, Mario, Borrelli, Anna, Pastorino, Cristina, Guidone, Daniela, Venturini, Arianna, Giraudo, Alessandro, Mandrup Bertozzi, Sine, Musante, Ilaria, Bertozzi, Fabio, Bandiera, Tiziano, Zara, Federico, Galietta, Luis J. V., Pedemonte, Nicoletta
Published in Int J Mol Sci (2021)

Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation

by Tomati, Valeria, Sondo, Elvira, Armirotti, Andrea, Caci, Emanuela, Pesce, Emanuela, Marini, Monica, Gianotti, Ambra, Ju Jeon, Young, Cilli, Michele, Pistorio, Angela, Mastracci, Luca, Ravazzolo, Roberto, Scholte, Bob, Ronai, Ze’ev, Galietta, Luis J. V., Pedemonte, Nicoletta
Published in Sci Rep (2015)

Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis

by Haque, A. K. M. Ashiqul, Dewerth, Alexander, Antony, Justin S., Riethmüller, Joachim, Schweizer, Georg R., Weinmann, Petra, Latifi, Ngadhnjim, Yasar, Hanzey, Pedemonte, Nicoletta, Sondo, Elvira, Weidensee, Brian, Ralhan, Anjali, Laval, Julie, Schlegel, Patrick, Seitz, Christian, Loretz, Brigitta, Lehr, Claus-Michael, Handgretinger, Rupert, Kormann, Michael S. D.
Published in Sci Rep (2018)

Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators

by Brindani, Nicoletta, Gianotti, Ambra, Giovani, Simone, Giacomina, Francesca, Di Fruscia, Paolo, Sorana, Federico, Bertozzi, Sine Mandrup, Ottonello, Giuliana, Goldoni, Luca, Penna, Ilaria, Russo, Debora, Summa, Maria, Bertorelli, Rosalia, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Galietta, Luis J. V., Bandiera, Tiziano, Pedemonte, Nicoletta, Bertozzi, Fabio
Published in J Med Chem (2020)