Menin regulates the function of hematopoietic stem cells and lymphoid progenitors

Por Maillard, Ivan, Chen, Ya-Xiong, Friedman, Ann, Yang, Yuqing, Tubbs, Anthony T., Shestova, Olga, Pear, Warren S., Hua, Xianxin
Publicado em 2009

The Developmental Regulator Protein Gon4l Associates with Protein YY1, Co-repressor Sin3a, and Histone Deacetylase 1 and Mediates Transcriptional Repression

Por Lu, Ping, Hankel, Isaiah L., Hostager, Bruce S., Swartzendruber, Julie A., Friedman, Ann D., Brenton, Janet L., Rothman, Paul B., Colgan, John D.
Publicado em 2011

T cell-specific Notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4(+) and CD8(+) T cells

Por Sandy, Ashley R., Chung, Jooho, Toubai, Tomomi, Shan, Gloria T., Tran, Ivy T., Friedman, Ann, Blackwell, Timothy S., Reddy, Pavan, King, Philip D., Maillard, Ivan
Publicado em 2013

Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease

Por Toubai, Tomomi, Sun, Yaping, Tawara, Isao, Friedman, Ann, Liu, Chen, Evers, Rebecca, Nieves, Evelyn, Malter, Chelsea, Chockley, Peter, Maillard, Ivan, Winandy, Susan, Reddy, Pavan
Publicado em 2011

Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation

Por Jones, Morgan, Osawa, Gail, Regal, Joshua A., Weinberg, Daniel N., Taggart, James, Kocak, Hande, Friedman, Ann, Ferguson, David O., Keegan, Catherine E., Maillard, Ivan
Publicado em 2013

Transient blockade of Delta-like Notch ligands prevents allograft rejection mediated by cellular and humoral mechanisms in a mouse model of heart transplantation

Por Wood, Sherri, Feng, Jiane, Chung, Jooho, Radojcic, Vedran, Sandy, Ashley R., Friedman, Ann, Shelton, Amy, Yan, Minhong, Siebel, Christian W., Bishop, D. Keith, Maillard, Ivan
Publicado no J Immunol (2015)

Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells

Por Jones, Morgan, Chase, Jennifer, Brinkmeier, Michelle, Xu, Jing, Weinberg, Daniel N., Schira, Julien, Friedman, Ann, Malek, Sami, Grembecka, Jolanta, Cierpicki, Tomasz, Dou, Yali, Camper, Sally A., Maillard, Ivan
Publicado no J Clin Invest (2015)

Notch signaling is a critical regulator of allogeneic CD4(+) T-cell responses mediating graft-versus-host disease

Por Zhang, Yi, Sandy, Ashley R., Wang, Jina, Radojcic, Vedran, Shan, Gloria T., Tran, Ivy T., Friedman, Ann, Kato, Koji, He, Shan, Cui, Shuaiying, Hexner, Elizabeth, Frank, Dale M., Emerson, Stephen G., Pear, Warren S., Maillard, Ivan
Publicado em 2011

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

Por Tran, Ivy T., Sandy, Ashley R., Carulli, Alexis J., Ebens, Christen, Chung, Jooho, Shan, Gloria T., Radojcic, Vedran, Friedman, Ann, Gridley, Thomas, Shelton, Amy, Reddy, Pavan, Samuelson, Linda C., Yan, Minhong, Siebel, Christian W., Maillard, Ivan
Publicado em 2013

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis

Por Lu, Ping, Hankel, Isaiah L., Knisz, Judit, Marquardt, Andreas, Chiang, Ming-Yi, Grosse, Johannes, Constien, Rainer, Meyer, Thomas, Schroeder, Andreas, Zeitlmann, Lutz, Al-Alem, Umaima, Friedman, Ann D., Elliott, Eric I., Meyerholz, David K., Waldschmidt, Thomas J., Rothman, Paul B., Colgan, John D.
Publicado em 2010

Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma

Por Wang, Yiwei, Huang, Dan, Chen, Kai-Yuan, Cui, Min, Wang, Weihuan, Huang, Xiaoran, Awadellah, Amad, Li, Qing, Friedman, Ann, Xin, William W., Di Martino, Luca, Cominelli, Fabio, Miron, Alex, Chan, Ricky, Fox, James, Xu, Yan, Shen, Xiling, Kalady, Mathew F., Markowitz, Sanford, Maillard, Ivan, Lowe, John B., Xin, Wei, Zhou, Lan
Publicado no Gastroenterology (2016)

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

Por Chung, Jooho, Ebens, Christen L., Perkey, Eric, Radojcic, Vedran, Koch, Ute, Scarpellino, Leonardo, Tong, Alexander, Allen, Frederick, Wood, Sherri, Feng, Jiane, Friedman, Ann, Granadier, David, Tran, Ivy T., Chai, Qian, Onder, Lucas, Yan, Minhong, Reddy, Pavan, Blazar, Bruce R., Huang, Alex Y., Brennan, Todd V., Bishop, D. Keith, Ludewig, Burkhard, Siebel, Christian W., Radtke, Freddy, Luther, Sanjiv A., Maillard, Ivan
Publicado no J Clin Invest (2017)