Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease

Host hematopoietically derived APCs play a vital role in the initiation of GVH responses. However, the APC autonomous molecular mechanisms that are critical for the induction of GVHD are not known. We report here that the Ikaros-Notch axis in host hematopoietically derived APCs regulates the severit...

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Autors principals: Toubai, Tomomi, Sun, Yaping, Tawara, Isao, Friedman, Ann, Liu, Chen, Evers, Rebecca, Nieves, Evelyn, Malter, Chelsea, Chockley, Peter, Maillard, Ivan, Winandy, Susan, Reddy, Pavan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139384/
https://ncbi.nlm.nih.gov/pubmed/21471527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324616
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