Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease

Host hematopoietically derived APCs play a vital role in the initiation of GVH responses. However, the APC autonomous molecular mechanisms that are critical for the induction of GVHD are not known. We report here that the Ikaros-Notch axis in host hematopoietically derived APCs regulates the severit...

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Bibliographische Detailangaben
Hauptverfasser: Toubai, Tomomi, Sun, Yaping, Tawara, Isao, Friedman, Ann, Liu, Chen, Evers, Rebecca, Nieves, Evelyn, Malter, Chelsea, Chockley, Peter, Maillard, Ivan, Winandy, Susan, Reddy, Pavan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
Schlagworte:
Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139384/
https://ncbi.nlm.nih.gov/pubmed/21471527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324616
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