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Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease
Host hematopoietically derived APCs play a vital role in the initiation of GVH responses. However, the APC autonomous molecular mechanisms that are critical for the induction of GVHD are not known. We report here that the Ikaros-Notch axis in host hematopoietically derived APCs regulates the severit...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139384/ https://ncbi.nlm.nih.gov/pubmed/21471527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324616 |
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