Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease

Host hematopoietically derived APCs play a vital role in the initiation of GVH responses. However, the APC autonomous molecular mechanisms that are critical for the induction of GVHD are not known. We report here that the Ikaros-Notch axis in host hematopoietically derived APCs regulates the severit...

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Main Authors: Toubai, Tomomi, Sun, Yaping, Tawara, Isao, Friedman, Ann, Liu, Chen, Evers, Rebecca, Nieves, Evelyn, Malter, Chelsea, Chockley, Peter, Maillard, Ivan, Winandy, Susan, Reddy, Pavan
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139384/
https://ncbi.nlm.nih.gov/pubmed/21471527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324616
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