Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease

Host hematopoietically derived APCs play a vital role in the initiation of GVH responses. However, the APC autonomous molecular mechanisms that are critical for the induction of GVHD are not known. We report here that the Ikaros-Notch axis in host hematopoietically derived APCs regulates the severit...

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Библиографические подробности
Главные авторы: Toubai, Tomomi, Sun, Yaping, Tawara, Isao, Friedman, Ann, Liu, Chen, Evers, Rebecca, Nieves, Evelyn, Malter, Chelsea, Chockley, Peter, Maillard, Ivan, Winandy, Susan, Reddy, Pavan
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2011
Предметы:
Transplantation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139384/
https://ncbi.nlm.nih.gov/pubmed/21471527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324616
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