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Blockade of individual Notch ligands and receptors controls graft-versus-host disease

Graft-versus-host disease (GVHD) is the main complication of allogeneic bone marrow transplantation. Current strategies to control GVHD rely on global immunosuppression. These strategies are incompletely effective and decrease the anticancer activity of the allogeneic graft. We previously identified...

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Détails bibliographiques
Auteurs principaux: Tran, Ivy T., Sandy, Ashley R., Carulli, Alexis J., Ebens, Christen, Chung, Jooho, Shan, Gloria T., Radojcic, Vedran, Friedman, Ann, Gridley, Thomas, Shelton, Amy, Reddy, Pavan, Samuelson, Linda C., Yan, Minhong, Siebel, Christian W., Maillard, Ivan
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613915/
https://ncbi.nlm.nih.gov/pubmed/23454750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65477
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