The novel mechanism of lenalidomide activity

Por Fink, Emma C., Ebert, Benjamin L.
Publicado no Blood (2015)

Saccharomyces cerevisiae Esc2p Interacts with Sir2p through a Small Ubiquitin-like Modifier (SUMO)-binding Motif and Regulates Transcriptionally Silent Chromatin in a Locus-depende...

Por Yu, Qun, Kuzmiak, Holly, Olsen, Lars, Kulkarni, Ajit, Fink, Emma, Zou, Yanfei, Bi, Xin
Publicado em 2010

Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome

Por Donovan, Katherine A, An, Jian, Nowak, Radosław P, Yuan, Jingting C, Fink, Emma C, Berry, Bethany C, Ebert, Benjamin L, Fischer, Eric S
Publicado no eLife (2018)

Crbn(I391V) is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice

Por Fink, Emma C., McConkey, Marie, Adams, Dylan N., Haldar, Saurav D., Kennedy, James A., Guirguis, Andrew A., Udeshi, Namrata D., Mani, D. R., Chen, Michelle, Liddicoat, Brian, Svinkina, Tanya, Nguyen, Andrew T., Carr, Steven A., Ebert, Benjamin L.
Publicado no Blood (2018)

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia

Por Järås, Marcus, Miller, Peter G., Chu, Lisa P., Puram, Rishi V., Fink, Emma C., Schneider, Rebekka K., Al-Shahrour, Fatima, Peña, Pablo, Breyfogle, L. Jordan, Hartwell, Kimberly A., McConkey, Marie E., Cowley, Glenn S., Root, David E., Kharas, Michael G., Mullally, Ann, Ebert, Benjamin L.
Publicado em 2014

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

Por Krönke, Jan, Fink, Emma C., Hollenbach, Paul W., MacBeth, Kyle J., Hurst, Slater N., Udeshi, Namrata D., Chamberlain, Philip P., Mani, D.R., Man, Hon Wah, Gandhi, Anita K., Svinkina, Tanya, Schneider, Rebekka K., McConkey, Marie, Järås, Marcus, Griffiths, Elizabeth, Wetzler, Meir, Bullinger, Lars, Cathers, Brian E., Carr, Steven A., Chopra, Rajesh, Ebert, Benjamin L.
Publicado no Nature (2015)