Crbn(I391V) is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice

Thalidomide and its derivatives, lenalidomide and pomalidomide, are clinically effective treatments for multiple myeloma and myelodysplastic syndrome with del(5q). These molecules lack activity in murine models, limiting investigation of their therapeutic activity or toxicity in vivo. Here, we repor...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Blood
मुख्य लेखकों: Fink, Emma C., McConkey, Marie, Adams, Dylan N., Haldar, Saurav D., Kennedy, James A., Guirguis, Andrew A., Udeshi, Namrata D., Mani, D. R., Chen, Michelle, Liddicoat, Brian, Svinkina, Tanya, Nguyen, Andrew T., Carr, Steven A., Ebert, Benjamin L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2018
विषय:
Myeloid Neoplasia
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172563/
https://ncbi.nlm.nih.gov/pubmed/30064974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-852798
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन