Role of Merlin/NF2 Inactivation in Tumor Biology

بواسطة Petrilli, Alejandra M., Fernández-Valle, Cristina
الحاوية / القاعدة Oncogene (2015)

Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis

بواسطة Petrilli, Alejandra M., Bott, Marga, Fernández-Valle, Cristina
منشور في 2013

Association of β1 Integrin with Focal Adhesion Kinase and Paxillin in Differentiating Schwann Cells

بواسطة Chen, Li-Mei, Bailey, Debora, Fernandez-Valle, Cristina
الحاوية / القاعدة J Neurosci (2000)

Actin Plays a Role in Both Changes in Cell Shape and Gene- Expression Associated with Schwann Cell Myelination

بواسطة Fernandez-Valle, Cristina, Gorman, Douglas, Gomez, Anna M., Bunge, Mary Bartlett
الحاوية / القاعدة J Neurosci (1997)

SCHWANNOMIN/MERLIN PROMOTES SCHWANN CELL ELONGATION AND INFLUENCES MYELIN SEGMENT LENGTH

بواسطة Thaxton, Courtney, Bott, Marga, Walker, Barbara, Sparrow, Nicklaus A., Lambert, Stephen, Fernandez-Valle, Cristina
منشور في 2010

Stability of the tumor suppressor merlin depends on its ability to bind paxillin LD3 and associate with β1 integrin and actin at the plasma membrane

بواسطة Manetti, Maria Elisa, Geden, Sandra, Bott, Marga, Sparrow, Nicklaus, Lambert, Stephen, Fernandez-Valle, Cristina
منشور في 2012

Node of Ranvier Formation on Motoneurons In Vitro

بواسطة Rumsey, John W, Das, Mainak, Stancescu, Maria, Bott, Marga, Fernandez-Valle, Cristina, Hickman, James J
منشور في 2009

A Xenograft Model of Vestibular Schwannoma and Hearing Loss

بواسطة Dinh, Christine T., Bracho, Olena, Mei, Christine, Bas, Esperanza, Fernandez-Valle, Cristina, Telischi, Fred, Liu, Xue-Zhong
الحاوية / القاعدة Otol Neurotol (2018)

LIM Domain Kinases as Potential Therapeutic Targets for Neurofibromatosis Type 2

بواسطة Petrilli, Alejandra, Copik, Alicja, Posadas, Michelle, Chang, Long-Sheng, Welling, D. Bradley, Giovannini, Marco, Fernández-Valle, Cristina
منشور في 2013

The Actin-Severing Protein Cofilin Is Downstream of Neuregulin Signaling and Is Essential For Schwann Cell Myelination

بواسطة Sparrow, Nicklaus, Manetti, Maria Elisa, Bott, Marga, Fabianac, Tiffany, Petrilli, Alejandra, Bates, Margaret Longest, Bunge, Mary Bartlett, Lambert, Stephen, Fernandez-Valle, Cristina
منشور في 2012

Genomics, Epigenetics, and Hearing Loss in Neurofibromatosis Type 2

بواسطة Dinh, Christine T., Nisenbaum, Eric, Chyou, Darius, Misztal, Carly, Yan, Denise, Mittal, Rahul, Young, Juan, Tekin, Mustafa, Telischi, Fred, Fernandez-Valle, Cristina, Liu, Xue-Zhong
الحاوية / القاعدة Otol Neurotol (2020)

Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival

بواسطة Pestoni, Jeanine C., Klingeman Plati, Stephani, Valdivia Camacho, Oliver D., Fuse, Marisa A., Onatunde, Maria, Sparrow, Nicklaus A., Karajannis, Matthias A., Fernández-Valle, Cristina, Franco, Maria Clara
الحاوية / القاعدة J Biol Chem (2019)

Chronic Inhibitory Effect of Riluzole on Trophic Factor Production

بواسطة Dennys, Cassandra N., Armstrong, JeNay, Levy, Mark, Byun, Youn Jung, Ramdial, Kristina R., Bott, Marga, Rossi, Fabian H., Fernández-Valle, Cristina, Franco, Maria Clara, Estevez, Alvaro G.
الحاوية / القاعدة Exp Neurol (2015)

A chemical biology approach identified PI3K as a potential therapeutic target for neurofibromatosis type 2

بواسطة Petrilli, Alejandra M, Fuse, Marisa A, Donnan, Mathew S, Bott, Marga, Sparrow, Nicklaus A, Tondera, Daniel, Huffziger, Julia, Frenzel, Corina, Malany, C Siobhan, Echeverri, Christophe J, Smith, Layton, Fernández-Valle, Cristina
منشور في 2014

Fluorescent Detection of Merlin-Deficient Schwann Cells and Primary Human Vestibular Schwannoma Cells Using Sodium Fluorescein

بواسطة Perez, Enrique R., Bracho, Olena, Ein, Liliana, Szczupak, Mikhaylo, Monje, Paula V., Fernandez-Valle, Cristina, Alshaiji, Abdulaziz, Ivan, Michael, Morcos, Jacques, Liu, Xue-Zhong, Hoffer, Michael, Eshraghi, Adrien, Angeli, Simon, Telischi, Fred, Dinh, Christine T.
الحاوية / القاعدة Otol Neurotol (2018)

Ponatinib promotes a G(1) cell-cycle arrest of merlin/NF2-deficient human schwann cells

بواسطة Petrilli, Alejandra M, Garcia, Jeanine, Bott, Marga, Plati, Stephani Klingeman, Dinh, Christine T, Bracho, Olena R, Yan, Denise, Zou, Bing, Mittal, Rahul, Telischi, Fred F, Liu, Xue-Zhong, Chang, Long-Sheng, Bradley, D Welling, Copik, Alicja J, Fernández-Valle, Cristina
الحاوية / القاعدة Oncotarget (2017)

Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2–associated schwannomas reveals differences in efficacy and drug resistance development

بواسطة Fuse, Marisa A, Dinh, Christine T, Vitte, Jeremie, Kirkpatrick, Joanna, Mindos, Thomas, Plati, Stephani Klingeman, Young, Juan I, Huang, Jie, Carlstedt, Annemarie, Franco, Maria Clara, Brnjos, Konstantin, Nagamoto, Jackson, Petrilli, Alejandra M, Copik, Alicja J, Soulakova, Julia N, Bracho, Olena, Yan, Denise, Mittal, Rahul, Shen, Rulong, Telischi, Fred F, Morrison, Helen, Giovannini, Marco, Liu, Xue-Zhong, Chang, Long-Sheng, Fernandez-Valle, Cristina
الحاوية / القاعدة Neuro Oncol (2019)

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

بواسطة Allaway, Robert, Angus, Steve P., Beauchamp, Roberta L., Blakeley, Jaishri O., Bott, Marga, Burns, Sarah S., Carlstedt, Annemarie, Chang, Long-Sheng, Chen, Xin, Clapp, D. Wade, Desouza, Patrick A., Erdin, Serkan, Fernandez-Valle, Cristina, Guinney, Justin, Gusella, James F., Haggarty, Stephen J., Johnson, Gary L., La Rosa, Salvatore, Morrison, Helen, Petrilli, Alejandra M., Plotkin, Scott R., Pratap, Abhishek, Ramesh, Vijaya, Sciaky, Noah, Stemmer-Rachamimov, Anat, Stuhlmiller, Tim J., Talkowski, Michael E., Welling, D. Bradley, Yates, Charles W., Zawistowski, Jon S., Zhao, Wen-Ning
الحاوية / القاعدة PLoS One (2018)

CTF Meeting 2012: Translation of the Basic Understanding of the Biology and Genetics of NF1, NF2, and Schwannomatosis Toward the Development of Effective Therapies

بواسطة Widemann, Brigitte C., Acosta, Maria T., Ammoun, Sylvia, Belzberg, Allan J., Bernards, Andre, Blakeley, Jaishri, Bretscher, Antony, Cichowski, Karen, Clapp, D. Wade, Dombi, Eva, Evans, Gareth D., Ferner, Rosalie, Fernandez-Valle, Cristina, Fisher, Michael J., Giovannini, Marco, Gutmann, David H., Hanemann, C. Oliver, Hennigan, Robert, Huson, Susan, Ingram, David, Kissil, Joe, Korf, Bruce R., Legius, Eric, Packer, Roger J., McClatchey, Andrea I, McCormick, Frank, North, Kathryn, Pehrsson, Minja, Plotkin, Scott R., Ramesh, Vijaya, Ratner, Nancy, Schirmer, Susann, Sherman, Larry, Schorry, Elizabeth, Stevenson, David, Stewart, Douglas R., Ullrich, Nicole, Bakker, Annette C., Morrison, Helen
منشور في 2014

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

بواسطة Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S. K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A. H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade
الحاوية / القاعدة PLoS One (2021)