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LIM Domain Kinases as Potential Therapeutic Targets for Neurofibromatosis Type 2
Neurofibromatosis Type 2 (NF2) is caused by mutations in the neurofibromatosis 2 (NF2) gene that encodes a tumor suppressor protein called merlin. NF2 is characterized by formation of multiple schwannomas, meningiomas and ependymomas. Merlin loss of function is associated with increased activity of...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016185/ https://ncbi.nlm.nih.gov/pubmed/23934191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.320 |
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