Antibiotic treatment and selection for glpK mutations in patients with active tuberculosis disease

著者: Vargas, Roger, Farhat, Maha R.
出版年 Proc Natl Acad Sci U S A (2020)

Globally diverse Mycobacterium tuberculosis resistance acquisition: a retrospective geographical and temporal analysis of whole genome sequences

著者: Ektefaie, Yasha, Dixit, Avika, Freschi, Luca, Farhat, Maha R
出版年 Lancet Microbe (2021)

Genome-wide discovery of epistatic loci affecting antibiotic resistance in Neisseria gonorrhoeae using evolutionary couplings

著者: Schubert, Benjamin, Maddamsetti, Rohan, Nyman, Jackson, Farhat, Maha R., Marks, Debora S.
出版年 Nat Microbiol (2018)

Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis

著者: Nebenzahl-Guimaraes, Hanna, Jacobson, Karen R., Farhat, Maha R., Murray, Megan B.
出版事項 2014

A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens

著者: Farhat, Maha R, Shapiro, B Jesse, Sheppard, Samuel K, Colijn, Caroline, Murray, Megan
出版年 Genome Med (2014)

Rifampicin and rifabutin resistance in 1003 Mycobacterium tuberculosis clinical isolates

著者: Farhat, Maha R, Sixsmith, Jaimie, Calderon, Roger, Hicks, Nathan D, Fortune, Sarah M, Murray, Megan
出版年 J Antimicrob Chemother (2019)

Fluoroquinolone Resistance Mutation Detection Is Equivalent to Culture-Based Drug Sensitivity Testing for Predicting Multidrug-Resistant Tuberculosis Treatment Outcome: A Retrospec...

著者: Farhat, Maha R, Jacobson, Karen R, Franke, Molly F, Kaur, Devinder, Murray, Megan, Mitnick, Carole D
出版年 Clin Infect Dis (2017)

A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis

著者: Karvellas, Constantine J, Farhat, Maha R, Sajjad, Imran, Mogensen, Simon S, Leung, Alexander A, Wald, Ron, Bagshaw, Sean M
出版事項 2011

Concordance of Mycobacterium tuberculosis Fluoroquinolone Resistance testing: implications for treatment

著者: Farhat, Maha R, Mitnick, Carole D, Franke, Molly F, Kaur, Devinder, Sloutsky, Alex, Murray, Megan, Jacobson, Karen R
出版年 Int J Tuberc Lung Dis (2015)

Gyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosis

著者: Farhat, Maha R., Jacobson, Karen R., Franke, Molly F., Kaur, Devinder, Sloutsky, Alex, Mitnick, Carole D., Murray, Megan
出版年 J Clin Microbiol (2016)

Association Between NEDD4L Variation and the Genetic Risk of Acute Appendicitis: A Multi-institutional Genome-Wide Association Study

著者: Gaitanidis, Apostolos, Kaafarani, Haytham M. A., Christensen, Mathias A., Breen, Kerry, Mendoza, April, Fagenholz, Peter J., Velmahos, George C., Farhat, Maha R.
出版年 JAMA Surg (2021)

Interpreting Expression Data with Metabolic Flux Models: Predicting Mycobacterium tuberculosis Mycolic Acid Production

著者: Colijn, Caroline, Brandes, Aaron, Zucker, Jeremy, Lun, Desmond S., Weiner, Brian, Farhat, Maha R., Cheng, Tan-Yun, Moody, D. Branch, Murray, Megan, Galagan, James E.
出版事項 2009

Whole genome sequencing identifies bacterial factors affecting transmission of multidrug-resistant tuberculosis in a high-prevalence setting

著者: Dixit, Avika, Freschi, Luca, Vargas, Roger, Calderon, Roger, Sacchettini, James, Drobniewski, Francis, Galea, Jerome T., Contreras, Carmen, Yataco, Rosa, Zhang, Zibiao, Lecca, Leonid, Kolokotronis, Sergios-Orestis, Mathema, Barun, Farhat, Maha R.
出版年 Sci Rep (2019)

GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions

著者: Farhat, Maha R., Freschi, Luca, Calderon, Roger, Ioerger, Thomas, Snyder, Matthew, Meehan, Conor J., de Jong, Bouke, Rigouts, Leen, Sloutsky, Alex, Kaur, Devinder, Sunyaev, Shamil, van Soolingen, Dick, Shendure, Jay, Sacchettini, Jim, Murray, Megan
出版年 Nat Commun (2019)

Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes

著者: Nebenzahl-Guimaraes, Hanna, van Laarhoven, Arjan, Farhat, Maha R., Koeken, Valerie A. C. M., Mandemakers, Jornt J., Zomer, Aldert, van Hijum, Sacha A. F. T., Netea, Mihai G., Murray, Megan, van Crevel, Reinout, van Soolingen, Dick
出版年 Am J Respir Crit Care Med (2017)

Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value

著者: Farhat, Maha R., Sultana, Razvan, Iartchouk, Oleg, Bozeman, Sam, Galagan, James, Sisk, Peter, Stolte, Christian, Nebenzahl-Guimaraes, Hanna, Jacobson, Karen, Sloutsky, Alexander, Kaur, Devinder, Posey, James, Kreiswirth, Barry N., Kurepina, Natalia, Rigouts, Leen, Streicher, Elizabeth M., Victor, Tommie C., Warren, Robin M., van Soolingen, Dick, Murray, Megan
出版年 Am J Respir Crit Care Med (2016)

The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

著者: Walker, Timothy M, Miotto, Paolo, Köser, Claudio U, Fowler, Philip W, Knaggs, Jeff, Iqbal, Zamin, Hunt, Martin, Chindelevitch, Leonid, Farhat, Maha R, Cirillo, Daniela Maria, Comas, Iñaki, Posey, James, Omar, Shaheed V, Peto, Timothy EA, Suresh, Anita, Uplekar, Swapna, Laurent, Sacha, Colman, Rebecca E, Nathanson, Carl-Michael, Zignol, Matteo, Walker, Ann Sarah, Crook, Derrick W, Ismail, Nazir, Rodwell, Timothy C
出版年 Lancet Microbe (2022)

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe

著者: Hunt, Martin, Bradley, Phelim, Lapierre, Simon Grandjean, Heys, Simon, Thomsit, Mark, Hall, Michael B., Malone, Kerri M., Wintringer, Penelope, Walker, Timothy M., Cirillo, Daniela M., Comas, Iñaki, Farhat, Maha R., Fowler, Phillip, Gardy, Jennifer, Ismail, Nazir, Kohl, Thomas A., Mathys, Vanessa, Merker, Matthias, Niemann, Stefan, Omar, Shaheed Vally, Sintchenko, Vitali, Smith, Grace, van Soolingen, Dick, Supply, Philip, Tahseen, Sabira, Wilcox, Mark, Arandjelovic, Irena, Peto, Tim E. A., Crook, Derrick W., Iqbal, Zamin
出版年 Wellcome Open Res (2019)

Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis

著者: Farhat, Maha R, Shapiro, B Jesse, Kieser, Karen J, Sultana, Razvan, Jacobson, Karen R, Victor, Thomas C, Warren, Robin M, Streicher, Elizabeth M, Calver, Alistair, Sloutsky, Alex, Kaur, Devinder, Posey, Jamie E, Plikaytis, Bonnie, Oggioni, Marco R, Gardy, Jennifer L, Johnston, James C, Rodrigues, Mabel, Tang, Patrick K C, Kato-Maeda, Midori, Borowsky, Mark L, Muddukrishna, Bhavana, Kreiswirth, Barry N, Kurepina, Natalia, Galagan, James, Gagneux, Sebastien, Birren, Bruce, Rubin, Eric J, Lander, Eric S, Sabeti, Pardis C, Murray, Megan
出版事項 2013

The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia

著者: Gröschel, Matthias I., Meehan, Conor J., Barilar, Ivan, Diricks, Margo, Gonzaga, Aitor, Steglich, Matthias, Conchillo-Solé, Oscar, Scherer, Isabell-Christin, Mamat, Uwe, Luz, Christian F., De Bruyne, Katrien, Utpatel, Christian, Yero, Daniel, Gibert, Isidre, Daura, Xavier, Kampmeier, Stefanie, Rahman, Nurdyana Abdul, Kresken, Michael, van der Werf, Tjip S., Alio, Ifey, Streit, Wolfgang R., Zhou, Kai, Schwartz, Thomas, Rossen, John W. A., Farhat, Maha R., Schaible, Ulrich E., Nübel, Ulrich, Rupp, Jan, Steinmann, Joerg, Niemann, Stefan, Kohl, Thomas A.
出版年 Nat Commun (2020)