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A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens

Whole genome sequencing is increasingly used to study phenotypic variation among infectious pathogens and to evaluate their relative transmissibility, virulence, and immunogenicity. To date, relatively little has been published on how and how many pathogen strains should be selected for studies asso...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Farhat, Maha R, Shapiro, B Jesse, Sheppard, Samuel K, Colijn, Caroline, Murray, Megan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256898/
https://ncbi.nlm.nih.gov/pubmed/25484920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0101-7
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