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A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens

Whole genome sequencing is increasingly used to study phenotypic variation among infectious pathogens and to evaluate their relative transmissibility, virulence, and immunogenicity. To date, relatively little has been published on how and how many pathogen strains should be selected for studies asso...

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Dettagli Bibliografici
Pubblicato in:Genome Med
Autori principali: Farhat, Maha R, Shapiro, B Jesse, Sheppard, Samuel K, Colijn, Caroline, Murray, Megan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256898/
https://ncbi.nlm.nih.gov/pubmed/25484920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0101-7
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