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A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens

Whole genome sequencing is increasingly used to study phenotypic variation among infectious pathogens and to evaluate their relative transmissibility, virulence, and immunogenicity. To date, relatively little has been published on how and how many pathogen strains should be selected for studies asso...

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Bibliografske podrobnosti
izdano v:Genome Med
Main Authors: Farhat, Maha R, Shapiro, B Jesse, Sheppard, Samuel K, Colijn, Caroline, Murray, Megan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256898/
https://ncbi.nlm.nih.gov/pubmed/25484920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0101-7
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