Gyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosis

Molecular diagnostics that rapidly and accurately predict resistance to fluoroquinolone drugs and especially later-generation agents promise to improve treatment outcomes for patients with multidrug-resistant tuberculosis and prevent the spread of disease. Mutations in the gyr genes are known to con...

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Bibliografiske detaljer
Udgivet i:J Clin Microbiol
Main Authors: Farhat, Maha R., Jacobson, Karen R., Franke, Molly F., Kaur, Devinder, Sloutsky, Alex, Mitnick, Carole D., Murray, Megan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Mycobacteriology and Aerobic Actinomycetes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767988/
https://ncbi.nlm.nih.gov/pubmed/26763957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02775-15
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