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Pyrosequencing for Rapid Detection of Mycobacterium tuberculosis Resistance to Rifampin, Isoniazid, and Fluoroquinolones

After isoniazid and rifampin (rifampicin), the next pivotal drug class in Mycobacterium tuberculosis treatment is the fluoroquinolone class. Mutations in resistance-determining regions (RDR) of the rpoB, katG, and gyrA genes occur with frequencies of 97%, 50%, and 85% among M. tuberculosis isolates...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bravo, Lulette Tricia C., Tuohy, Marion J., Ang, Concepcion, Destura, Raul V., Mendoza, Myrna, Procop, Gary W., Gordon, Steven M., Hall, Geraldine S., Shrestha, Nabin K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786679/
https://ncbi.nlm.nih.gov/pubmed/19846642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01229-09
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