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Rifampicin and rifabutin resistance in 1003 Mycobacterium tuberculosis clinical isolates

OBJECTIVES: Drug-resistant TB remains a public health challenge. Rifamycins are among the most potent anti-TB drugs. They are known to target the RpoB subunit of RNA polymerase; however, our understanding of how rifamycin resistance is genetically encoded remains incomplete. Here we investigated rpo...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Farhat, Maha R, Sixsmith, Jaimie, Calderon, Roger, Hicks, Nathan D, Fortune, Sarah M, Murray, Megan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524487/
https://ncbi.nlm.nih.gov/pubmed/30793747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz048
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