Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation

door Ma, Yafeng, Li, Ang, Faller, William J., Libertini, Silvana, Fiorito, Florencia, Gillespie, David A., Sansom, Owen J., Yamashiro, Shigeko, Machesky, Laura M.
Gepubliceerd in 2013

A microRNA DNA methylation signature for human cancer metastasis

door Lujambio, Amaia, Calin, George A., Villanueva, Alberto, Ropero, Santiago, Sánchez-Céspedes, Montserrat, Blanco, David, Montuenga, Luis M., Rossi, Simona, Nicoloso, Milena S., Faller, William J., Gallagher, William M., Eccles, Suzanne A., Croce, Carlo M., Esteller, Manel
Gepubliceerd in 2008

A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis

door Kumar, Namit, Srivillibhuthur, Manasa, Joshi, Shilpy, Walton, Katherine D., Zhou, Anbo, Faller, William J., Perekatt, Ansu O., Sansom, Owen J., Gumucio, Deborah L., Xing, Jinchuan, Bonder, Edward M., Gao, Nan, White, Eileen, Verzi, Michael P.
Gepubliceerd in Development (2016)

Melanoma Cells Break Down LPA to Establish Local Gradients That Drive Chemotactic Dispersal

door Muinonen-Martin, Andrew J., Susanto, Olivia, Zhang, Qifeng, Smethurst, Elizabeth, Faller, William J., Veltman, Douwe M., Kalna, Gabriela, Lindsay, Colin, Bennett, Dorothy C., Sansom, Owen J., Herd, Robert, Jones, Robert, Machesky, Laura M., Wakelam, Michael J. O., Knecht, David A., Insall, Robert H.
Gepubliceerd in 2014

Fascin Is Regulated by Slug, Promotes Progression of Pancreatic Cancer in Mice, and Is Associated With Patient Outcomes

door Li, Ang, Morton, Jennifer P., Ma, YaFeng, Karim, Saadia A., Zhou, Yan, Faller, William J., Woodham, Emma F., Morris, Hayley T., Stevenson, Richard P., Juin, Amelie, Jamieson, Nigel B., MacKay, Colin J., Carter, C. Ross, Leung, Hing Y., Yamashiro, Shigeko, Blyth, Karen, Sansom, Owen J., Machesky, Laura M.
Gepubliceerd in 2014

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia

door Rai, Taranjit Singh, Cole, John J., Nelson, David M., Dikovskaya, Dina, Faller, William J., Vizioli, Maria Grazia, Hewitt, Rachael N., Anannya, Orchi, McBryan, Tony, Manoharan, Indrani, van Tuyn, John, Morrice, Nicholas, Pchelintsev, Nikolay A., Ivanov, Andre, Brock, Claire, Drotar, Mark E., Nixon, Colin, Clark, William, Sansom, Owen J., Anderson, Kurt I., King, Ayala, Blyth, Karen, Adams, Peter D.
Gepubliceerd in Genes Dev (2014)

mTORC1 mediated translational elongation limits intestinal tumour initiation and growth

door Faller, William J., Jackson, Thomas J., Knight, John RP, Ridgway, Rachel A., Jamieson, Thomas, Karim, Saadia A., Jones, Carolyn, Radulescu, Sorina, Huels, David J., Myant, Kevin B., Dudek, Kate M., Casey, Helen A., Scopelliti, Alessandro, Cordero, Julia B., Vidal, Marcos, Pende, Mario, Ryazanov, Alexey G., Sonenberg, Nahum, Meyuhas, Oded, Hall, Michael N., Bushell, Martin, Willis, Anne E., Sansom, Owen J.
Gepubliceerd in Nature (2014)

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis

door Leach, Joshua D. G., Vlahov, Nikola, Tsantoulis, Petros, Ridgway, Rachel A., Flanagan, Dustin J., Gilroy, Kathryn, Sphyris, Nathalie, Vázquez, Ester G., Vincent, David F., Faller, William J., Hodder, Michael C., Raven, Alexander, Fey, Sigrid, Najumudeen, Arafath K., Strathdee, Douglas, Nixon, Colin, Hughes, Mark, Clark, William, Shaw, Robin, van Hooff, Sander R., Huels, David J., Medema, Jan Paul, Barry, Simon T., Frame, Margaret C., Unciti-Broceta, Asier, Leedham, Simon J., Inman, Gareth J., Jackstadt, Rene, Thompson, Barry J., Campbell, Andrew D., Tejpar, Sabine, Sansom, Owen J.
Gepubliceerd in Nat Commun (2021)

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

door Lindsay, Colin R., Lawn, Samuel, Campbell, Andrew D., Faller, William J., Rambow, Florian, Mort, Richard L., Timpson, Paul, Li, Ang, Cammareri, Patrizia, Ridgway, Rachel A., Morton, Jennifer P., Doyle, Brendan, Hegarty, Shauna, Rafferty, Mairin, Murphy, Ian G., McDermott, Enda W., Sheahan, Kieran, Pedone, Katherine, Finn, Alexander J., Groben, Pamela A., Thomas, Nancy E., Hao, Honglin, Carson, Craig, Norman, Jim C, Machesky, Laura M, Gallagher, William M., Jackson, Ian J., Van Kempen, Leon, Beermann, Friedrich, Der, Channing, Larue, Lionel, Welch, Heidi C., Ozanne, Brad W., Sansom, Owen J.
Gepubliceerd in 2011

MNK inhibition sensitizes KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-MYC expression

door Knight, John R. P., Alexandrou, Constantinos, Skalka, George L., Vlahov, Nikola, Pennel, Kathryn, Officer, Leah, Teodosio, Ana, Kanellos, Georgios, Gay, David M., May-Wilson, Sebastian, Smith, Ewan M., Najumudeen, Arafath K., Gilroy, Kathryn, Ridgway, Rachel A., Flanagan, Dustin J., Smith, Rachael C. L., McDonald, Laura, MacKay, Craig, Cheasty, Anne, McArthur, Kerri, Stanway, Emma, Leach, Joshua D., Jackstadt, Rene, Waldron, Joseph A., Campbell, Andrew D., Vlachogiannis, Georgios, Valeri, Nicola, Haigis, Kevin M., Sonenberg, Nahum, Proud, Christopher G., Jones, Neil P., Swarbrick, Martin E., McKinnon, Heather J., Faller, William J., Le Quesne, John, Edwards, Joanne, Willis, Anne E., Bushell, Martin, Sansom, Owen J.
Gepubliceerd in Cancer Discov (2021)