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P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

Metastases are the major cause of death from melanoma, a skin cancer which has the fastest rising incidence of any malignancy in the Western world. Molecular pathways that drive melanoblast migration in development are believed to underpin the movement and ultimately the metastasis of melanoma. Here...

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Detalhes bibliográficos
Main Authors: Lindsay, Colin R., Lawn, Samuel, Campbell, Andrew D., Faller, William J., Rambow, Florian, Mort, Richard L., Timpson, Paul, Li, Ang, Cammareri, Patrizia, Ridgway, Rachel A., Morton, Jennifer P., Doyle, Brendan, Hegarty, Shauna, Rafferty, Mairin, Murphy, Ian G., McDermott, Enda W., Sheahan, Kieran, Pedone, Katherine, Finn, Alexander J., Groben, Pamela A., Thomas, Nancy E., Hao, Honglin, Carson, Craig, Norman, Jim C, Machesky, Laura M, Gallagher, William M., Jackson, Ian J., Van Kempen, Leon, Beermann, Friedrich, Der, Channing, Larue, Lionel, Welch, Heidi C., Ozanne, Brad W., Sansom, Owen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400057/
https://ncbi.nlm.nih.gov/pubmed/22109529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1560
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