Insight into the Cooperation of P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) at the Blood-Brain Barrier: A Case Study Examining Sorafenib Efflux Clearance

著者: Agarwal, Sagar, Elmquist, William F.
出版事項 2012

“INVESTIGATION OF THE MICELLAR EFFECT OF PLURONIC P85 ON P-GLYCOPROTEIN INHIBITION: CELL ACCUMULATION AND EQUILIBRIUM DIALYSIS STUDIES”

著者: SHAIK, NAVEED, GIRI, NAGDEEP, ELMQUIST, WILLIAM F.
出版事項 2009

Brain Distribution of Cediranib Is Limited by Active Efflux at the Blood-Brain Barrier

著者: Wang, Tianli, Agarwal, Sagar, Elmquist, William F.
出版事項 2012

Brain Distribution and Bioavailability of Elacridar after Different Routes of Administration in the Mouse

著者: Sane, Ramola, Agarwal, Sagar, Elmquist, William F.
出版事項 2012

Brain Efflux Index To Investigate the Influence of Active Efflux on Brain Distribution of Pemetrexed and Methotrexate

著者: Li, Li, Agarwal, Sagar, Elmquist, William F.
出版事項 2013

Interactions of Pluronic Block Copolymers on P-gp Efflux Activity: Experience With HIV-1 Protease Inhibitors

著者: SHAIK, NAVEED, PAN, GUOYU, ELMQUIST, WILLIAM F.
出版年 J Pharm Sci (2008)

Determination of Cediranib in Mouse Plasma and Brain Tissue Using High-Performance Liquid Chromatography-Mass Spectrometry

著者: Wang, Tianli, Oberoi, Rajneet K., Elmquist, William F.
出版事項 2011

Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability

著者: Sane, Ramola, Mittapalli, Rajendar K., Elmquist, William F.
出版事項 2013

EMBR-28. CNS DISTRIBUTIONAL KINETICS OF PANOBINOSTAT IN THE MOUSE

著者: Zhang, Wenqiu, Mohammad, Afroz, Sirianni, Rachael, Elmquist, William
出版年 Neuro Oncol (2021)

Pharmacokinetic Assessment of Efflux Transport in Sunitinib Distribution to the Brain

著者: Oberoi, Rajneet K., Mittapalli, Rajendar K., Elmquist, William F.
出版事項 2013

OCT2 and MATE1 Provide Bi-directional Agmatine Transport

著者: Winter, Tate N., Elmquist, William F., Fairbanks, Carolyn A.
出版年 Mol Pharm (2010)

Utilizing transmembrane convection to enhance solute sampling and delivery by microdialysis: theory and in vitro validation

著者: Bungay, Peter M., Wang, Tianli, Yang, Hua, Elmquist, William F.
出版事項 2010

The Role of the Breast Cancer Resistance Protein (ABCG2) in the Distribution of Sorafenib to the Brain

著者: Agarwal, Sagar, Sane, Ramola, Ohlfest, John R., Elmquist, William F.
出版事項 2011

Breast Cancer Resistance Protein and P-glycoprotein in Brain Cancer: Two Gatekeepers Team Up

著者: Agarwal, Sagar, Hartz, Anika M.S., Elmquist, William F., Bauer, Björn
出版事項 2011

Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on the Brain Distribution of a Novel BRAF Inhibitor: Vemurafenib (PLX4032)

著者: Mittapalli, Rajendar K., Vaidhyanathan, Shruthi, Sane, Ramola, Elmquist, William F.
出版事項 2012

Saturable Active Efflux by P-Glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier Leads to Nonlinear Distribution of Elacridar to the Central Nervous System

著者: Sane, Ramola, Agarwal, Sagar, Mittapalli, Rajendar K., Elmquist, William F.
出版事項 2013

Bayesian Approach to Estimate AUC, Partition Coefficient and Drug Targeting Index for Studies with Serial Sacrifice Design

著者: Wang, Tianli, Baron, Kyle, Zhong, Wei, Brundage, Richard, Elmquist, William
出版事項 2013

Drug Delivery to Melanoma Brain Metastases: Can Current Challenges Lead to New Opportunities?

著者: Gampa, Gautham, Vaidhyanathan, Shruthi, Sarkaria, Jann N., Elmquist, William F.
出版年 Pharmacol Res (2017)

HGG-13. BRAIN DISTRIBUTION AND CLEARANCE OF ALISERTIB IS LIMITED BY PGP AND BCRP EFFLUX PUMPS AND DEPENDENT UPON DELIVERY METHOD

著者: Power, Erica, Oh, Juhee, Zhang, Liang, Elmquist, William, Daniels, David
出版年 Neuro Oncol (2021)

Mechanisms Limiting Distribution of the Threonine-Protein Kinase B-RaF(V600E) Inhibitor Dabrafenib to the Brain: Implications for the Treatment of Melanoma Brain Metastases

著者: Mittapalli, Rajendar K., Vaidhyanathan, Shruthi, Dudek, Arkadiusz Z., Elmquist, William F.
出版事項 2013