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“INVESTIGATION OF THE MICELLAR EFFECT OF PLURONIC P85 ON P-GLYCOPROTEIN INHIBITION: CELL ACCUMULATION AND EQUILIBRIUM DIALYSIS STUDIES”
The objective of this study was: (1) to characterize the P-gp inhibitory effect of different concentrations of Pluronic P85 on anti-HIV-1drug cellular accumulation, and (2) to investigate the relationship between cellular accumulation and free fraction of drug. Cellular accumulation studies in MDCKI...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755653/ https://ncbi.nlm.nih.gov/pubmed/19283769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.21723 |
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