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Drug Delivery to Melanoma Brain Metastases: Can Current Challenges Lead to New Opportunities?
Melanoma has a high propensity to metastasize to the brain, and patients with melanoma brain metastases (MBM) have an extremely poor prognosis. The recent approval of several molecularly-targeted agents (e.g., BRAF, MEK inhibitors) and biologics (anti-CTLA-4, anti-PD-1 and anti-PD-L1 antibodies) has...
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| Publicado no: | Pharmacol Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565722/ https://ncbi.nlm.nih.gov/pubmed/28634084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.06.008 |
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