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Barriers to Effective Drug Treatment for Brain Metastases: A Multifactorial Problem in the Delivery of Precision Medicine

The treatment of metastatic lesions in the brain represents a serious unmet medical need in the field of neurooncology. Even though many effective compounds have demonstrated success in treating peripheral (non-CNS) tumors with targeted agents, one aspect of this lack of success in the brain may be...

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Pubblicato in:Pharm Res
Autori principali: Kim, Minjee, Kizilbash, Sani H., Laramy, Janice K., Gampa, Gautham, Parrish, Karen E., Sarkaria, Jann N., Elmquist, William F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700736/
https://ncbi.nlm.nih.gov/pubmed/30003344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2455-9
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