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Drug Delivery to Melanoma Brain Metastases: Can Current Challenges Lead to New Opportunities?

Melanoma has a high propensity to metastasize to the brain, and patients with melanoma brain metastases (MBM) have an extremely poor prognosis. The recent approval of several molecularly-targeted agents (e.g., BRAF, MEK inhibitors) and biologics (anti-CTLA-4, anti-PD-1 and anti-PD-L1 antibodies) has...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pharmacol Res
Päätekijät: Gampa, Gautham, Vaidhyanathan, Shruthi, Sarkaria, Jann N., Elmquist, William F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565722/
https://ncbi.nlm.nih.gov/pubmed/28634084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.06.008
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