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Brain Distribution and Bioavailability of Elacridar after Different Routes of Administration in the Mouse

The objective of this study was to determine the bioavailability and disposition of elacridar (GF120918; N-(4-(2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl)phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide) in plasma and brain after various routes of administration in the mous...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sane, Ramola, Agarwal, Sagar, Elmquist, William F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400790/
https://ncbi.nlm.nih.gov/pubmed/22611067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.045930
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