Chargement en cours...

Brain Distribution of Cediranib Is Limited by Active Efflux at the Blood-Brain Barrier

Cediranib is an orally active tyrosine kinase inhibitor that targets the vascular endothelial growth factor receptor family. Because of its potent antiangiogenic and antitumor activities, cediranib has been evaluated for therapy in glioma, a primary brain tumor. This study investigated the influence...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wang, Tianli, Agarwal, Sagar, Elmquist, William F.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336816/
https://ncbi.nlm.nih.gov/pubmed/22323823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.190488
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!