Cargando...

Brain Distribution of Cediranib Is Limited by Active Efflux at the Blood-Brain Barrier

Cediranib is an orally active tyrosine kinase inhibitor that targets the vascular endothelial growth factor receptor family. Because of its potent antiangiogenic and antitumor activities, cediranib has been evaluated for therapy in glioma, a primary brain tumor. This study investigated the influence...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wang, Tianli, Agarwal, Sagar, Elmquist, William F.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336816/
https://ncbi.nlm.nih.gov/pubmed/22323823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.190488
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!