Insight into the Cooperation of P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) at the Blood-Brain Barrier: A Case Study Examining Sorafenib Efflux Clearance

Tekijä Agarwal, Sagar, Elmquist, William F.
Julkaistu 2012

“INVESTIGATION OF THE MICELLAR EFFECT OF PLURONIC P85 ON P-GLYCOPROTEIN INHIBITION: CELL ACCUMULATION AND EQUILIBRIUM DIALYSIS STUDIES”

Tekijä SHAIK, NAVEED, GIRI, NAGDEEP, ELMQUIST, WILLIAM F.
Julkaistu 2009

Brain Distribution of Cediranib Is Limited by Active Efflux at the Blood-Brain Barrier

Tekijä Wang, Tianli, Agarwal, Sagar, Elmquist, William F.
Julkaistu 2012

Brain Distribution and Bioavailability of Elacridar after Different Routes of Administration in the Mouse

Tekijä Sane, Ramola, Agarwal, Sagar, Elmquist, William F.
Julkaistu 2012

Brain Efflux Index To Investigate the Influence of Active Efflux on Brain Distribution of Pemetrexed and Methotrexate

Tekijä Li, Li, Agarwal, Sagar, Elmquist, William F.
Julkaistu 2013

Interactions of Pluronic Block Copolymers on P-gp Efflux Activity: Experience With HIV-1 Protease Inhibitors

Tekijä SHAIK, NAVEED, PAN, GUOYU, ELMQUIST, WILLIAM F.
Julkaisussa J Pharm Sci (2008)

Determination of Cediranib in Mouse Plasma and Brain Tissue Using High-Performance Liquid Chromatography-Mass Spectrometry

Tekijä Wang, Tianli, Oberoi, Rajneet K., Elmquist, William F.
Julkaistu 2011

Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability

Tekijä Sane, Ramola, Mittapalli, Rajendar K., Elmquist, William F.
Julkaistu 2013

EMBR-28. CNS DISTRIBUTIONAL KINETICS OF PANOBINOSTAT IN THE MOUSE

Tekijä Zhang, Wenqiu, Mohammad, Afroz, Sirianni, Rachael, Elmquist, William
Julkaisussa Neuro Oncol (2021)

Pharmacokinetic Assessment of Efflux Transport in Sunitinib Distribution to the Brain

Tekijä Oberoi, Rajneet K., Mittapalli, Rajendar K., Elmquist, William F.
Julkaistu 2013

OCT2 and MATE1 Provide Bi-directional Agmatine Transport

Tekijä Winter, Tate N., Elmquist, William F., Fairbanks, Carolyn A.
Julkaisussa Mol Pharm (2010)

Utilizing transmembrane convection to enhance solute sampling and delivery by microdialysis: theory and in vitro validation

Tekijä Bungay, Peter M., Wang, Tianli, Yang, Hua, Elmquist, William F.
Julkaistu 2010

The Role of the Breast Cancer Resistance Protein (ABCG2) in the Distribution of Sorafenib to the Brain

Tekijä Agarwal, Sagar, Sane, Ramola, Ohlfest, John R., Elmquist, William F.
Julkaistu 2011

Breast Cancer Resistance Protein and P-glycoprotein in Brain Cancer: Two Gatekeepers Team Up

Tekijä Agarwal, Sagar, Hartz, Anika M.S., Elmquist, William F., Bauer, Björn
Julkaistu 2011

Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on the Brain Distribution of a Novel BRAF Inhibitor: Vemurafenib (PLX4032)

Tekijä Mittapalli, Rajendar K., Vaidhyanathan, Shruthi, Sane, Ramola, Elmquist, William F.
Julkaistu 2012

Saturable Active Efflux by P-Glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier Leads to Nonlinear Distribution of Elacridar to the Central Nervous System

Tekijä Sane, Ramola, Agarwal, Sagar, Mittapalli, Rajendar K., Elmquist, William F.
Julkaistu 2013

Bayesian Approach to Estimate AUC, Partition Coefficient and Drug Targeting Index for Studies with Serial Sacrifice Design

Tekijä Wang, Tianli, Baron, Kyle, Zhong, Wei, Brundage, Richard, Elmquist, William
Julkaistu 2013

Drug Delivery to Melanoma Brain Metastases: Can Current Challenges Lead to New Opportunities?

Tekijä Gampa, Gautham, Vaidhyanathan, Shruthi, Sarkaria, Jann N., Elmquist, William F.
Julkaisussa Pharmacol Res (2017)

HGG-13. BRAIN DISTRIBUTION AND CLEARANCE OF ALISERTIB IS LIMITED BY PGP AND BCRP EFFLUX PUMPS AND DEPENDENT UPON DELIVERY METHOD

Tekijä Power, Erica, Oh, Juhee, Zhang, Liang, Elmquist, William, Daniels, David
Julkaisussa Neuro Oncol (2021)

Mechanisms Limiting Distribution of the Threonine-Protein Kinase B-RaF(V600E) Inhibitor Dabrafenib to the Brain: Implications for the Treatment of Melanoma Brain Metastases

Tekijä Mittapalli, Rajendar K., Vaidhyanathan, Shruthi, Dudek, Arkadiusz Z., Elmquist, William F.
Julkaistu 2013