Sister chromatid junctions in the hyperthermophilic archaeon Sulfolobus solfataricus

Por Robinson, Nicholas P, Blood, Katherine A, McCallum, Simon A, Edwards, Paul A W, Bell, Stephen D
Publicado em 2007

The Relative Timing of Mutations in a Breast Cancer Genome

Por Newman, Scott, Howarth, Karen D., Greenman, Chris D., Bignell, Graham R., Tavaré, Simon, Edwards, Paul A. W.
Publicado em 2013

Single-molecule analysis of genome rearrangements in cancer

Por Pole, Jessica C. M., McCaughan, Frank, Newman, Scott, Howarth, Karen D., Dear, Paul H., Edwards, Paul A. W.
Publicado em 2011

Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis

Por Paterson, Anna L., Weaver, Jamie M.J., Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C., Edwards, Paul A.W.
Publicado no BMC Genomics (2015)

Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles

Por Howarth, Karen D., Pole, Jessica C.M., Beavis, Juliet C., Batty, Elizabeth M., Newman, Scott, Bignell, Graham R., Edwards, Paul A.W.
Publicado em 2011

Whole-genome sequencing of nine esophageal adenocarcinoma cell lines

Por Contino, Gianmarco, Eldridge, Matthew D., Secrier, Maria, Bower, Lawrence, Fels Elliott, Rachael, Weaver, Jamie, Lynch, Andy G., Edwards, Paul A.W., Fitzgerald, Rebecca C.
Publicado no F1000Res (2016)

Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation

Por Mason, Bethany, Flach, Susanne, Teixeira, Felipe R., Manzano Garcia, Raquel, Rueda, Oscar M., Abraham, Jean E., Caldas, Carlos, Edwards, Paul A. W., Laman, Heike
Publicado no Cell Mol Life Sci (2019)

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement

Por Abdel-Rahman, Wael M., Katsura, Kanade, Rens, Willem, Gorman, Patricia A., Sheer, Denise, Bicknell, David, Bodmer, Walter F., Arends, Mark J., Wyllie, Andrew H., Edwards, Paul A. W.
Publicado em 2001

Estimation of rearrangement phylogeny for cancer genomes

Por Greenman, Chris D., Pleasance, Erin D., Newman, Scott, Yang, Fengtang, Fu, Beiyuan, Nik-Zainal, Serena, Jones, David, Lau, King Wai, Carter, Nigel, Edwards, Paul A.W., Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Publicado em 2012

NRG1 fusions in breast cancer

Por Howarth, Karen D., Mirza, Tashfina, Cooke, Susanna L., Chin, Suet-Feung, Pole, Jessica C., Turro, Ernest, Eldridge, Matthew D., Garcia, Raquel Manzano, Rueda, Oscar M., Boursnell, Chris, Abraham, Jean E., Caldas, Carlos, Edwards, Paul A. W.
Publicado no Breast Cancer Res (2021)

Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity

Por Kim, Jiyoung, Villadsen, René, Sørlie, Therese, Fogh, Louise, Grønlund, Signe Z., Fridriksdottir, Agla J., Kuhn, Irene, Rank, Fritz, Wielenga, Vera Timmermans, Solvang, Hiroko, Edwards, Paul A. W., Børresen-Dale, Anne-Lise, Rønnov-Jessen, Lone, Bissell, Mina J., Petersen, Ole William
Publicado em 2012

Complex multi-enhancer contacts captured by Genome Architecture Mapping (GAM)

Por Beagrie, Robert A., Scialdone, Antonio, Schueler, Markus, Kraemer, Dorothee C.A., Chotalia, Mita, Xie, Sheila Q., Barbieri, Mariano, de Santiago, Inês, Lavitas, Liron-Mark, Branco, Miguel R., Fraser, James, Dostie, Josée, Game, Laurence, Dillon, Niall, Edwards, Paul A.W., Nicodemi, Mario, Pombo, Ana
Publicado no Nature (2017)

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

Por Bignell, Graham R., Santarius, Thomas, Pole, Jessica C.M., Butler, Adam P., Perry, Janet, Pleasance, Erin, Greenman, Chris, Menzies, Andrew, Taylor, Sheila, Edkins, Sarah, Campbell, Peter, Quail, Michael, Plumb, Bob, Matthews, Lucy, McLay, Kirsten, Edwards, Paul A.W., Rogers, Jane, Wooster, Richard, Futreal, P. Andrew, Stratton, Michael R.
Publicado em 2007

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

Por Campbell, Peter J, Stephens, Philip J, Pleasance, Erin D, O’Meara, Sarah, Li, Heng, Santarius, Thomas, Stebbings, Lucy A, Leroy, Catherine, Edkins, Sarah, Hardy, Claire, Teague, Jon W, Menzies, Andrew, Goodhead, Ian, Turner, Daniel J, Clee, Christopher M, Quail, Michael A, Cox, Antony, Brown, Clive, Durbin, Richard, Hurles, Matthew E, Edwards, Paul A W, Bignell, Graham R, Stratton, Michael R, Futreal, P Andrew
Publicado em 2008

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance

Por Secrier, Maria, Li, Xiaodun, de Silva, Nadeera, Eldridge, Matthew D., Contino, Gianmarco, Bornschein, Jan, MacRae, Shona, Grehan, Nicola, O’Donovan, Maria, Miremadi, Ahmad, Yang, Tsun-Po, Bower, Lawrence, Chettouh, Hamza, Crawte, Jason, Galeano-Dalmau, Núria, Grabowska, Anna, Saunders, John, Underwood, Tim, Waddell, Nicola, Barbour, Andrew P., Nutzinger, Barbara, Achilleos, Achilleas, Edwards, Paul A. W., Lynch, Andy G., Tavaré, Simon, Fitzgerald, Rebecca C.
Publicado no Nat Genet (2016)

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

Por Chandra, Tamir, Kirschner, Kristina, Thuret, Jean-Yves, Pope, Benjamin D., Ryba, Tyrone, Newman, Scott, Ahmed, Kashif, Samarajiwa, Shamith A., Salama, Rafik, Carroll, Thomas, Stark, Rory, Janky, Rekin’s, Narita, Masako, Xue, Lixiang, Chicas, Agustin, Nũnez, Sabrina, Janknecht, Ralf, Hayashi-Takanaka, Yoko, Wilson, Michael D., Marshall, Aileen, Odom, Duncan T., Babu, M. Madan, Bazett-Jones, David P., Tavaré, Simon, Edwards, Paul A.W., Lowe, Scott W., Kimura, Hiroshi, Gilbert, David M., Narita, Masashi
Publicado em 2012

Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis

Por Weaver, Jamie M.J., Ross-Innes, Caryn S., Shannon, Nicholas, Lynch, Andy G., Forshew, Tim, Barbera, Mariagnese, Murtaza, Muhammed, Ong, Chin-Ann J., Lao-Sirieix, Pierre, Dunning, Mark J, Smith, Laura, Smith, Mike L., Anderson, Charlotte L., Carvalho, Benilton, O’Donovan, Maria, Underwood, Timothy J., May, Andrew P, Grehan, Nicola, Hardwick, Richard, Davies, Jim, Oloumi, Arusha, Aparicio, Sam, Caldas, Carlos, Eldridge, Matthew D., Edwards, Paul A.W., Rosenfeld, Nitzan, Tavaré, Simon, Fitzgerald, Rebecca C
Publicado em 2014