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NRG1 fusions in breast cancer
BACKGROUND: NRG1 gene fusions may be clinically actionable, since cancers carrying the fusion transcripts can be sensitive to tyrosine kinase inhibitors. The NRG1 gene encodes ligands for the HER2(ERBB2)-ERBB3 heterodimeric receptor tyrosine kinase, and the gene fusions are thought to lead to autocr...
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| Publicado no: | Breast Cancer Res |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7788813/ https://ncbi.nlm.nih.gov/pubmed/33413557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-020-01377-5 |
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