Complex multi-enhancer contacts captured by Genome Architecture Mapping (GAM)

The organization of the genome in the nucleus and the interactions of genes with their regulatory elements are key features of transcriptional control and their disruption can cause disease. We developed a novel genome-wide method, Genome Architecture Mapping (GAM), for measuring chromatin contacts,...

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Publicado no:Nature
Main Authors: Beagrie, Robert A., Scialdone, Antonio, Schueler, Markus, Kraemer, Dorothee C.A., Chotalia, Mita, Xie, Sheila Q., Barbieri, Mariano, de Santiago, Inês, Lavitas, Liron-Mark, Branco, Miguel R., Fraser, James, Dostie, Josée, Game, Laurence, Dillon, Niall, Edwards, Paul A.W., Nicodemi, Mario, Pombo, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366070/
https://ncbi.nlm.nih.gov/pubmed/28273065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21411
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