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Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles
Reciprocal chromosome translocations are often not exactly reciprocal. Most familiar are deletions at the breakpoints, up to megabases in extent. We describe here the opposite phenomenon—duplication of tens or hundreds of kilobases at the breakpoint junction, so that the same sequence is present on...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065700/ https://ncbi.nlm.nih.gov/pubmed/21252201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.114116.110 |
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