Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors

Using a combination of array comparative genomic hybridization, mate pair and cloned sequences, and FISH analyses, we have identified in multiple myeloma cell lines and tumors a novel and recurrent type of genomic rearrangement, i.e. interchromosomal rearrangements (translocations or insertions) and...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Demchenko, Yulia, Roschke, Anna, Chen, Wei-Dong, Asmann, Yan, Bergsagel, Peter Leif, Kuehl, Walter Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041460/
https://ncbi.nlm.nih.gov/pubmed/27353332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw527
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items