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Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors

Using a combination of array comparative genomic hybridization, mate pair and cloned sequences, and FISH analyses, we have identified in multiple myeloma cell lines and tumors a novel and recurrent type of genomic rearrangement, i.e. interchromosomal rearrangements (translocations or insertions) and...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Demchenko, Yulia, Roschke, Anna, Chen, Wei-Dong, Asmann, Yan, Bergsagel, Peter Leif, Kuehl, Walter Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041460/
https://ncbi.nlm.nih.gov/pubmed/27353332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw527
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