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Complex IGH Rearrangements in Multiple Myeloma: Frequent Detection Discrepancies Among Three Different Probe Sets

Primary IGH translocations involving seven recurrent partner loci and oncogenes are present in about 40% of multiple myeloma tumors. Secondary IGH rearrangements, which occur in a smaller fraction of tumors, usually are complex structures, including insertions or translocations that can involve thre...

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Autors principals: Kim, Gina Y., Gabrea, Ana, Demchenko, Yulia N., Bergsagel, Leif, Roschke, Anna V., Kuehl, W. Michael
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011190/
https://ncbi.nlm.nih.gov/pubmed/24585545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22158
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