Mutant BRAF upregulates MCL-1 to confer apoptosis resistance that is reversed by MCL-1 antagonism and cobimetinib in colorectal cancer

Por Kawakami, Hisato, Huang, Shengbing, Pal, Krishnendu, Dutta, Shamit K., Mukhopadhyay, Debabrata, Sinicrope, Frank A.
Publicado no Mol Cancer Ther (2016)

Insulin Receptor Substrate-2 Mediated Insulin-Like Growth Factor-1 Receptor Overexpression in Pancreatic Adenocarcinoma Through PKC δ

Por Kwon, Junhye, Stephan, Susann, Mukhopadhyay, Ananya, Muders, Michael H., Dutta, Shamit K., Lau, Julie S., Mukhopadhyay, Debabrata
Publicado em 2009

NHERF-2 maintains endothelial homeostasis

Por Bhattacharya, Resham, Wang, Enfeng, Dutta, Shamit K., Vohra, Pawan K., E, Guangqi, Prakash, Y. S., Mukhopadhyay, Debabrata
Publicado em 2012

VEGF exerts an angiogenesis-independent function in cancer cells to promote their malignant progression

Por Cao, Ying, E, Guangqi, Wang, Enfeng, Pal, Krishnendu, Dutta, Shamit K., Bar-Sagi, Dafna, Mukhopadhyay, Debabrata
Publicado em 2012

Neuropilin-1 Modulates p53/Caspases Axis to Promote Endothelial Cell Survival

Por Wang, Ling, Dutta, Shamit K., Kojima, Tatsuyoshi, Xu, Xiaolei, Khosravi-Far, Roya, Ekker, Stephen C., Mukhopadhyay, Debabrata
Publicado em 2007

Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer

Por Patra, Chitta Ranjan, Rupasinghe, Chamila N., Dutta, Shamit K, Bhattacharya, Santanu, Wang, Enfeng, Spaller, Mark R., Mukhopadhyay, Debabrata
Publicado em 2012

Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury

Por Vohra, Pawan K., Hoeppner, Luke H., Sagar, Gunisha, Dutta, Shamit K., Misra, Sanjay, Hubmayr, Rolf D., Mukhopadhyay, Debabrata
Publicado em 2012

Neuropilin-1 Mediates Divergent R-Smad Signaling and the Myofibroblast Phenotype

Por Cao, Ying, Szabolcs, Annamaria, Dutta, Shamit K., Yaqoob, Usman, Jagavelu, Kumaravelu, Wang, Ling, Leof, Edward B., Urrutia, Raul A., Shah, Vijay H., Mukhopadhyay, Debabrata
Publicado em 2010

Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer

Por Pal, Krishnendu, Cao, Ying, Gaisina, Irina N., Bhattacharya, Santanu, Dutta, Shamit K., Wang, Enfeng, Gunosewoyo, Hendra, Kozikowski, Alan P., Billadeau, Daniel D., Mukhopadhyay, Debabrata
Publicado em 2013

Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function

Por Sinha, Sutapa, Mondal, Gourish, Hwang, Eun Ju, Han, Da Woon, Dutta, Shamit K., Iyer, Seethalakshmi, Karumanchi, S. Ananth, Kim, Keun Il, Couch, Fergus J., Mukhopadhyay, Debabrata
Publicado em 2011

Pathogenesis of Pancreatic Cancer Exosome-Induced Lipolysis in Adipose Tissue

Por Sagar, Gunisha, Sah, Raghuwansh P., Javeed, Naureen, Dutta, Shamit K, Smyrk, Thomas C, Lau, Julie S, Giorgadze, Nino, Tchkonia, Tamar, Kirkland, James, Chari, Suresh T, Mukhopadhyay, Debabrata
Publicado no Gut (2015)

Pancreatic Cancer-derived Exosomes Causes Paraneoplastic β-cell Dysfunction

Por Javeed, Naureen, Sagar, Gunisha, Dutta, Shamit K., Smyrk, Thomas C., Lau, Julie S., Bhattacharya, Santanu, Truty, Mark, Petersen, Gloria M., Kaufman, Randal J., Chari, Suresh T., Mukhopadhyay, Debabrata
Publicado no Clin Cancer Res (2014)

Immunosuppressive CD14(+)HLA-DR(lo/neg) monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes

Por Javeed, Naureen, Gustafson, Michael P., Dutta, Shamit K., Lin, Yi, Bamlet, William R., Oberg, Ann L., Petersen, Gloria M., Chari, Suresh T., Dietz, Allan B., Mukhopadhyay, Debabrata
Publicado no Oncoimmunology (2016)

Metformin suppresses pancreatic tumor growth with inhibition of NFκB/STAT3 inflammatory signaling

Por Tan, Xiang-Lin, Bhattacharyya, Kalyan K., Dutta, Shamit K., Bamlet, William R., Rabe, Kari G., Wang, Enfeng, Smyrk, Thomas C., Oberg, Ann L., Petersen, Gloria M., Mukhopadhyay, Debabrata
Publicado no Pancreas (2015)

Inhibition of endoglin-GIPC interaction inhibits pancreatic cancer cell growth

Por Pal, Krishnendu, Pletnev, Alexandre A., Dutta, Shamit K., Wang, Enfeng, Zhao, Ruizhi, Baral, Aradhita, Yadav, Vinod Kumar, Aggarwal, Suruchi, Krishnaswamy, Soundararajan, Alkharfy, Khalid M., Chowdhury, Shantanu, Spaller, Mark R., Mukhopadhyay, Debabrata
Publicado no Mol Cancer Ther (2014)

GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways

Por Bhattacharya, Santanu, Pal, Krishnendu, Sharma, Anil K., Dutta, Shamit K., Lau, Julie S., Yan, Irene K., Wang, Enfeng, Elkhanany, Ahmed, Alkharfy, Khalid M., Sanyal, Arunik, Patel, Tushar C., Chari, Suresh T., Spaller, Mark R., Mukhopadhyay, Debabrata
Publicado no PLoS One (2014)

Targeting GIPC/Synectin in Pancreatic Cancer Inhibits Tumor Growth

Por Muders, Michael H., Vohra, Pawan K., Dutta, Shamit K, Wang, Enfeng, Ikeda, Yasuhiro, Wang, Ling, Udugamasooriya, D. Gomika, Memic, Adnan, Rupashinghe, Chamila N., Baretton, Gustavo B., Aust, Daniela E., Langer, Silke, Datta, Kaustubh, Simons, Michael, Spaller, Mark R., Mukhopadhyay, Debabrata
Publicado em 2009

CARDIOMYOPATHY AND WORSENED ISCHEMIC HEART FAILURE IN SM22-α CRE-MEDIATED NEUROPILIN-1 NULL MICE: DYSREGULATION OF PGC1α AND MITOCHONDRIAL HOMEOSTASIS

Por Wang, Ying, Cao, Ying, Yamada, Satsuki, Thirunavukkarasu, Mahesh, Nin, Veronica, Joshi, Mandip, Rishi, Muhammed T., Bhattacharya, Santanu, Camacho-Pereira, Juliana, Sharma, Anil K., Shameer, Khader, Kocher, Jean-Pierre A., Sanchez, Juan A, Wang, Enfeng, Hoeppner, Luke H., Dutta, Shamit K., Leof1, Edward B., Shah, Vijay, Claffey, Kevin P., Chini, Eduardo, Simons, Michael, Terzic, Andre, Maulik, Nilanjana, Mukhopadhyay, Debabrata
Publicado no Arterioscler Thromb Vasc Biol (2015)