Inhibition of endoglin-GIPC interaction inhibits pancreatic cancer cell growth

Endoglin, a 180 kDa disulfide-linked homodimeric, transmembrane receptor protein mostly expressed in tumor-associated endothelial cells, is an endogenous binding partner of GAIP-interacting protein, C terminus (GIPC). Endoglin functions as a co-receptor of TβRII that binds Transforming Growth Factor...

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Publicado en:Mol Cancer Ther
Autores principales: Pal, Krishnendu, Pletnev, Alexandre A., Dutta, Shamit K., Wang, Enfeng, Zhao, Ruizhi, Baral, Aradhita, Yadav, Vinod Kumar, Aggarwal, Suruchi, Krishnaswamy, Soundararajan, Alkharfy, Khalid M., Chowdhury, Shantanu, Spaller, Mark R., Mukhopadhyay, Debabrata
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229952/
https://ncbi.nlm.nih.gov/pubmed/25125675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0291
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