Synchronous inhibition of mTOR and VEGF/NRP1 axis impedes tumor growth and metastasis in renal cancer

Clear cell renal cell carcinoma (ccRCC) is known for its highly vascular phenotype which is associated with elevated expression of vascular endothelial growth factor A (VEGF), also known as vascular permeability factor (VPF). Accordingly, VEGF has been an attractive target for antiangiogenic therapi...

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Bibliografske podrobnosti
izdano v:NPJ Precis Oncol
Main Authors: Pal, Krishnendu, Madamsetty, Vijay Sagar, Dutta, Shamit Kumar, Wang, Enfeng, Angom, Ramcharan Singh, Mukhopadhyay, Debabrata
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895165/
https://ncbi.nlm.nih.gov/pubmed/31840081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0105-2
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