Synchronous inhibition of mTOR and VEGF/NRP1 axis impedes tumor growth and metastasis in renal cancer

Clear cell renal cell carcinoma (ccRCC) is known for its highly vascular phenotype which is associated with elevated expression of vascular endothelial growth factor A (VEGF), also known as vascular permeability factor (VPF). Accordingly, VEGF has been an attractive target for antiangiogenic therapi...

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Bibliografiske detaljer
Udgivet i:NPJ Precis Oncol
Main Authors: Pal, Krishnendu, Madamsetty, Vijay Sagar, Dutta, Shamit Kumar, Wang, Enfeng, Angom, Ramcharan Singh, Mukhopadhyay, Debabrata
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895165/
https://ncbi.nlm.nih.gov/pubmed/31840081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0105-2
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