CARDIOMYOPATHY AND WORSENED ISCHEMIC HEART FAILURE IN SM22-α CRE-MEDIATED NEUROPILIN-1 NULL MICE: DYSREGULATION OF PGC1α AND MITOCHONDRIAL HOMEOSTASIS

OBJECTIVE: Neuropilin-1 (NRP-1) is a multi-domain membrane receptor involved in angiogenesis and development of neuronal circuits, however, the role of NRP-1 in cardiovascular pathophysiology remains elusive. APPROACH AND RESULTS: In this study, we first observed that deletion of NRP-1 induced perox...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Arterioscler Thromb Vasc Biol
Main Authors: Wang, Ying, Cao, Ying, Yamada, Satsuki, Thirunavukkarasu, Mahesh, Nin, Veronica, Joshi, Mandip, Rishi, Muhammed T., Bhattacharya, Santanu, Camacho-Pereira, Juliana, Sharma, Anil K., Shameer, Khader, Kocher, Jean-Pierre A., Sanchez, Juan A, Wang, Enfeng, Hoeppner, Luke H., Dutta, Shamit K., Leof1, Edward B., Shah, Vijay, Claffey, Kevin P., Chini, Eduardo, Simons, Michael, Terzic, Andre, Maulik, Nilanjana, Mukhopadhyay, Debabrata
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441604/
https://ncbi.nlm.nih.gov/pubmed/25882068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305566
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