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Immunosuppressive CD14(+)HLA-DR(lo/neg) monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes

Immunological strategies to treat pancreatic cancer offer new therapeutic approaches to improve patient outcomes. Understanding alterations in the immune systems of pancreatic cancer patients will likely lead to advances in immunotherapy for the disease. We profiled peripheral blood leukocytes from...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Javeed, Naureen, Gustafson, Michael P., Dutta, Shamit K., Lin, Yi, Bamlet, William R., Oberg, Ann L., Petersen, Gloria M., Chari, Suresh T., Dietz, Allan B., Mukhopadhyay, Debabrata
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283619/
https://ncbi.nlm.nih.gov/pubmed/28197368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1252013
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