Immunosuppressive CD14(+)HLA-DR(lo/neg) monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes

Immunological strategies to treat pancreatic cancer offer new therapeutic approaches to improve patient outcomes. Understanding alterations in the immune systems of pancreatic cancer patients will likely lead to advances in immunotherapy for the disease. We profiled peripheral blood leukocytes from...

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Détails bibliographiques
Publié dans:Oncoimmunology
Auteurs principaux: Javeed, Naureen, Gustafson, Michael P., Dutta, Shamit K., Lin, Yi, Bamlet, William R., Oberg, Ann L., Petersen, Gloria M., Chari, Suresh T., Dietz, Allan B., Mukhopadhyay, Debabrata
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283619/
https://ncbi.nlm.nih.gov/pubmed/28197368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1252013
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