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Insulin Receptor Substrate-2 Mediated Insulin-Like Growth Factor-1 Receptor Overexpression in Pancreatic Adenocarcinoma Through PKC δ

Pancreatic adenocarcinoma (PCA) is an almost invariably fatal disease. Recently, it has been shown by several groups as well as ours that IGF-1 receptor (IGF-1R) overexpression is related to higher proliferation, survival, angiogenesis, and highly invasive pancreatic tumors. Several studies have bee...

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Hlavní autoři: Kwon, Junhye, Stephan, Susann, Mukhopadhyay, Ananya, Muders, Michael H., Dutta, Shamit K., Lau, Julie S., Mukhopadhyay, Debabrata
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705142/
https://ncbi.nlm.nih.gov/pubmed/19190347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1328
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