Inhibition of Tumor Cells Interacting with Stromal Cells by Xanthones Isolated from a Costa Rican Penicillium sp.

Por Cao, Shugeng, McMillin, Douglas W., Tamayo, Giselle, Delmore, Jake, Mitsiades, Constantine S., Clardy, Jon
Publicado em 2012

Methyljasmonate Displays In Vitro and In Vivo Activity against Multiple Myeloma Cells

Por Klippel, Steffen, Jakubikova, Jana, Delmore, Jake, Ooi, Melissa, McMillin, Douglas, Kastritis, Efstathios, Laubach, Jacob, Richardson, Paul G., Anderson, Kenneth C., Mitsiades, Constantine S.
Publicado no Br J Haematol (2012)

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias

Por O’Connor, Robert, Ooi, Melissa G., Meiller, Justine, Jakubikova, Jana, Klippel, Steffen, Delmore, Jake, Richardson, Paul, Anderson, Kenneth, Clynes, Martin, Mitsiades, Constantine S., O’Gorman, Peter
Publicado no Cancer Chemother Pharmacol (2013)

Microenvironmental Influence on Pre-Clinical Activity of Polo-Like Kinase Inhibition in Multiple Myeloma: Implications for Clinical Translation

Por McMillin, Douglas W., Delmore, Jake, Negri, Joseph, Ooi, Melissa, Klippel, Steffen, Miduturu, Chandrasekhar V., Gray, Nathanael S., Richardson, Paul G., Anderson, Kenneth C., Kung, Andrew L., Mitsiades, Constantine S.
Publicado em 2011

Compartment-specific bioluminescence imaging platform for the high-throughput evaluation of antitumor immune function

Por McMillin, Douglas W., Delmore, Jake, Negri, Joseph M., Vanneman, Matthew, Koyama, Shohei, Schlossman, Robert L., Munshi, Nikhil C., Laubach, Jacob, Richardson, Paul G., Dranoff, Glenn, Anderson, Kenneth C., Mitsiades, Constantine S.
Publicado em 2012

In vitro anti-myeloma activity of the Aurora kinase inhibitor VE-465

Por Negri, Joseph M., McMillin, Douglas W., Delmore, Jake, Mitsiades, Nicholas, Hayden, Patrick, Klippel, Steffen, Hideshima, Teru, Chauhan, Dharminder, Munshi, Nikhil C., Buser, Carolyn A., Pollard, John, Richardson, Paul G., Anderson, Kenneth C., Mitsiades, Constantine S.
Publicado em 2009

Molecular and cellular effects of NEDD8 activating enzyme (NAE) inhibition in myeloma

Por McMillin, Douglas W., Jacobs, Hannah M., Delmore, Jake E., Buon, Leutz, Hunter, Zachary R., Monrose, Val, Yu, Jie, Smith, Peter G., Richardson, Paul G., Anderson, Kenneth C., Treon, Steven P., Kung, Andrew L., Mitsiades, Constantine S.
Publicado em 2012

Molecular and cellular effects of multi-targeted CDK inhibition in myeloma: Biological and clinical implications

Por McMillin, Douglas W., Delmore, Jake, Negri, Joseph, Buon, Leutz, Jacobs, Hannah M., Laubach, Jacob, Jakubikova, Jana, Ooi, Melissa, Hayden, Patrick, Schlossman, Robert, Munshi, Nikhil C., Lengauer, Christoph, Richardson, Paul G., Anderson, Kenneth C., Mitsiades, Constantine S.
Publicado em 2011

Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anti-cancer drug activity

Por McMillin, Douglas W., Delmore, Jake, Weisberg, Ellen, Negri, Joseph M., Geer, D. Corey, Klippel, Steffen, Mitsiades, Nicholas, Schlossman, Robert L., Munshi, Nikhil C., Kung, Andrew L., Griffin, James D., Richardson, Paul G., Anderson, Kenneth C., Mitsiades, Constantine S.
Publicado em 2010

Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications

Por Jakubikova, Jana, Adamia, Sophia, Kost-Alimova, Maria, Klippel, Steffen, Cervi, David, Daley, John F., Cholujova, Dana, Kong, Sun-Young, Leiba, Merav, Blotta, Simona, Ooi, Melissa, Delmore, Jake, Laubach, Jacob, Richardson, Paul G., Sedlak, Jan, Anderson, Kenneth C., Mitsiades, Constantine S.
Publicado em 2011

Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma

Por Jakubikova, Jana, Cervi, David, Ooi, Melissa, Kim, Kihyun, Nahar, Sabikun, Klippel, Steffen, Cholujova, Dana, Leiba, Merav, Daley, John F., Delmore, Jake, Negri, Joseph, Blotta, Simona, McMillin, Douglas W., Hideshima, Teru, Richardson, Paul G., Sedlak, Jan, Anderson, Kenneth C., Mitsiades, Constantine S.
Publicado em 2011

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

Por Delmore, Jake E., Issa, Ghayas C., Lemieux, Madeleine E., Rahl, Peter B., Shi, Junwei, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M., Qi, Jun, Chesi, Marta, Schinzel, Anna, McKeown, Michael R., Heffernan, Timothy P., Vakoc, Christopher R., Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G., Young, Richard A., Hahn, William C., Anderson, Kenneth C., Kung, Andrew L., Bradner, James E., Mitsiades, Constantine S.
Publicado em 2011

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

Por Esquejo, Ryan M., Salatto, Christopher T., Delmore, Jake, Albuquerque, Bina, Reyes, Allan, Shi, Yuji, Moccia, Rob, Cokorinos, Emily, Peloquin, Matthew, Monetti, Mara, Barricklow, Jason, Bollinger, Eliza, Smith, Brennan K., Day, Emily A., Nguyen, Chuong, Geoghegan, Kieran F., Kreeger, John M., Opsahl, Alan, Ward, Jessica, Kalgutkar, Amit S., Tess, David, Butler, Lynne, Shirai, Norimitsu, Osborne, Timothy F., Steinberg, Gregory R., Birnbaum, Morris J., Cameron, Kimberly O., Miller, Russell A.
Publicado no EBioMedicine (2018)