A carregar...

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias

PURPOSE: Bortezomib is an important agent in multiple myeloma treatment, but resistance in cell lines and patients has been described. The main mechanisms of resistance described in cancer fall into one of two categories, pharmacokinetic resistance (PK), e.g. over expression of drug efflux pumps and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: O’Connor, Robert, Ooi, Melissa G., Meiller, Justine, Jakubikova, Jana, Klippel, Steffen, Delmore, Jake, Richardson, Paul, Anderson, Kenneth, Clynes, Martin, Mitsiades, Constantine S., O’Gorman, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414393/
https://ncbi.nlm.nih.gov/pubmed/23589314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2136-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!