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Inhibition of Tumor Cells Interacting with Stromal Cells by Xanthones Isolated from a Costa Rican Penicillium sp.

CR1642D, an endophytic isolate of Penicillium sp. collected from a Costa Rican rainforest, was identified through a high-throughput approach to identify natural products with enhanced anti-tumor activity in the context of tumor-stromal interactions. Bioassay-guided separation led to the identificati...

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Detalhes bibliográficos
Main Authors: Cao, Shugeng, McMillin, Douglas W., Tamayo, Giselle, Delmore, Jake, Mitsiades, Constantine S., Clardy, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338863/
https://ncbi.nlm.nih.gov/pubmed/22458669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np2009863
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