Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications

Recurrence of multiple myeloma (MM) after therapy suggests the presence of tumor-initiating subpopulations. In our study, we performed flow cytometry–based Hoechst 33342 staining to evaluate the existence of a MM population with stem-like features known as side population (SP) cells. SP cells exhibi...

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Detalhes bibliográficos
Main Authors: Jakubikova, Jana, Adamia, Sophia, Kost-Alimova, Maria, Klippel, Steffen, Cervi, David, Daley, John F., Cholujova, Dana, Kong, Sun-Young, Leiba, Merav, Blotta, Simona, Ooi, Melissa, Delmore, Jake, Laubach, Jacob, Richardson, Paul G., Sedlak, Jan, Anderson, Kenneth C., Mitsiades, Constantine S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099565/
https://ncbi.nlm.nih.gov/pubmed/21321360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-267344
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